2dzo
From Proteopedia
(Difference between revisions)
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<StructureSection load='2dzo' size='340' side='right'caption='[[2dzo]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='2dzo' size='340' side='right'caption='[[2dzo]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2dzo]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2dzo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DZO FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2dzn|2dzn]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2dzn|2dzn]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dzo OCA], [https://pdbe.org/2dzo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dzo RCSB], [https://www.ebi.ac.uk/pdbsum/2dzo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dzo ProSAT], [https://www.topsan.org/Proteins/RSGI/2dzo TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/PSD10_YEAST PSD10_YEAST]] Acts as a chaperone during the assembly of the 26S proteasome, specifically of the 19S regulatory complex (RC) and appears to have an overlapping role with RPN14.<ref>PMID:19412159</ref> <ref>PMID:19446322</ref> <ref>PMID:9714768</ref> [[https://www.uniprot.org/uniprot/PRS6B_YEAST PRS6B_YEAST]] The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 17:19, 15 December 2021
Crystal structure analysis of yeast Nas6p complexed with the proteasome subunit, rpt3
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