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2zp2
From Proteopedia
(Difference between revisions)
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==C-terminal domain of KipI from Bacillus subtilis== | ==C-terminal domain of KipI from Bacillus subtilis== | ||
| - | <StructureSection load='2zp2' size='340' side='right' caption='[[2zp2]], [[Resolution|resolution]] 3.01Å' scene=''> | + | <StructureSection load='2zp2' size='340' side='right'caption='[[2zp2]], [[Resolution|resolution]] 3.01Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2zp2]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2zp2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZP2 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">kipI ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">kipI ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zp2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zp2 OCA], [https://pdbe.org/2zp2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zp2 RCSB], [https://www.ebi.ac.uk/pdbsum/2zp2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zp2 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/KIPI_BACSU KIPI_BACSU]] Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase A affecting the ATP/ADP reactions and not the phosphotransferase functions of this domain. The inhibition is noncompetitive with respect to ATP. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Vibrio subtilis ehrenberg 1835]] | [[Category: Vibrio subtilis ehrenberg 1835]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Jacques, D A]] | [[Category: Jacques, D A]] | ||
[[Category: Langley, D B]] | [[Category: Langley, D B]] | ||
Revision as of 17:34, 15 December 2021
C-terminal domain of KipI from Bacillus subtilis
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