1g2i

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[[Image:1g2i.gif|left|200px]]
[[Image:1g2i.gif|left|200px]]
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{{Structure
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|PDB= 1g2i |SIZE=350|CAPTION= <scene name='initialview01'>1g2i</scene>, resolution 2.00&Aring;
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The line below this paragraph, containing "STRUCTURE_1g2i", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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|ACTIVITY=
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|GENE= PH1704 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=53953 Pyrococcus horikoshii])
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03134 GATase1_PfpI_like]</span>
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{{STRUCTURE_1g2i| PDB=1g2i | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g2i OCA], [http://www.ebi.ac.uk/pdbsum/1g2i PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1g2i RCSB]</span>
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'''CRYSTAL STRUCTURE OF A NOVEL INTRACELLULAR PROTEASE FROM PYROCOCCUS HORIKOSHII AT 2 A RESOLUTION'''
'''CRYSTAL STRUCTURE OF A NOVEL INTRACELLULAR PROTEASE FROM PYROCOCCUS HORIKOSHII AT 2 A RESOLUTION'''
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[[Category: Kim, R.]]
[[Category: Kim, R.]]
[[Category: Kim, S H.]]
[[Category: Kim, S H.]]
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[[Category: atp-independent intracellular protease]]
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[[Category: Atp-independent intracellular protease]]
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[[Category: berkeley structural genomics center]]
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[[Category: Berkeley structural genomics center]]
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[[Category: bsgc structure funded by nih]]
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[[Category: Bsgc structure funded by nih]]
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[[Category: catalytical triad]]
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[[Category: Catalytical triad]]
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[[Category: cysteine protease]]
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[[Category: Cysteine protease]]
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[[Category: intracellular protease]]
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[[Category: Intracellular protease]]
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[[Category: nucleophile elbow]]
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[[Category: Nucleophile elbow]]
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[[Category: pfpi]]
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[[Category: Pfpi]]
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[[Category: protease]]
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[[Category: Protease]]
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[[Category: protein structure initiative]]
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[[Category: Protein structure initiative]]
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[[Category: psi]]
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[[Category: Psi]]
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[[Category: structural genomic]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 17:03:27 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:35:10 2008''
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Revision as of 14:03, 2 May 2008

Image:1g2i.gif

Template:STRUCTURE 1g2i

CRYSTAL STRUCTURE OF A NOVEL INTRACELLULAR PROTEASE FROM PYROCOCCUS HORIKOSHII AT 2 A RESOLUTION


Overview

The intracellular protease from Pyrococcus horikoshii (PH1704) and PfpI from Pyrococcus furiosus are members of a class of intracellular proteases that have no sequence homology to any other known protease family. We report the crystal structure of PH1704 at 2.0-A resolution. The protease is tentatively identified as a cysteine protease based on the presence of cysteine (residue 100) in a nucleophile elbow motif. In the crystal, PH1704 forms a hexameric ring structure, and the active sites are formed at the interfaces between three pairs of monomers.

About this Structure

1G2I is a Single protein structure of sequence from Pyrococcus horikoshii. Full crystallographic information is available from OCA.

Reference

Crystal structure of an intracellular protease from Pyrococcus horikoshii at 2-A resolution., Du X, Choi IG, Kim R, Wang W, Jancarik J, Yokota H, Kim SH, Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14079-84. PMID:11114201 Page seeded by OCA on Fri May 2 17:03:27 2008

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