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2j7t
From Proteopedia
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<StructureSection load='2j7t' size='340' side='right'caption='[[2j7t]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='2j7t' size='340' side='right'caption='[[2j7t]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2j7t]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2j7t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J7T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J7T FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=274:(3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-1H-PYRROL-2-YL}METHYLENE)-N-METHYL-2-OXOINDOLINE-5-SULFONAMIDE'>274</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=274:(3Z)-N-(3-CHLOROPHENYL)-3-({3,5-DIMETHYL-4-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-1H-PYRROL-2-YL}METHYLENE)-N-METHYL-2-OXOINDOLINE-5-SULFONAMIDE'>274</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j7t OCA], [https://pdbe.org/2j7t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j7t RCSB], [https://www.ebi.ac.uk/pdbsum/2j7t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j7t ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
Revision as of 11:13, 5 January 2022
Crystal structure of human serine threonine kinase-10 bound to SU11274
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Categories: Human | Large Structures | Non-specific serine/threonine protein kinase | Arrowsmith, C H | Das, S | Debreczeni, J | Delft, F von | Edwards, A | Eswaran, J | Fedorov, O | Gorrec, F | Knapp, S | Papagrigoriou, E | Pike, A C.W | Rellos, P | Savitsky, P | Sobott, F | Sundstrom, M | Turnbull, A P | Ugochukwa, E | Umeano, C C | Watt, S | Weigelt, J | Atp-binding | Cell cycle progression | Disease mutation | Kinase | Nucleotide- binding | Phosphorylation | Serine/threonine- protein kinase | Transferase

