1ej6

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<SX load='1ej6' size='340' side='right' viewer='molstar' caption='[[1ej6]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
<SX load='1ej6' size='340' side='right' viewer='molstar' caption='[[1ej6]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ej6]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Reovirus_sp. Reovirus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJ6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1EJ6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ej6]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Reovirus_sp. Reovirus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EJ6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1ej6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ej6 OCA], [http://pdbe.org/1ej6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ej6 RCSB], [http://www.ebi.ac.uk/pdbsum/1ej6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ej6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ej6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ej6 OCA], [https://pdbe.org/1ej6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ej6 RCSB], [https://www.ebi.ac.uk/pdbsum/1ej6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ej6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LMBD2_REOVD LMBD2_REOVD]] Outer capsid protein involved in mRNA capping. Catalyzes the last 3 enzymatic activities for formation of the 5' cap structure on the viral plus-strand transcripts, namely the RNA guanylyltransferase, RNA-7N- and RNA-2'O-methyltransferase activities. [[http://www.uniprot.org/uniprot/SIGM2_REOVD SIGM2_REOVD]] Inner capsid (core) component. [[http://www.uniprot.org/uniprot/LMBD1_REOVD LMBD1_REOVD]] Inner capsid (core) component. Displays NTPase, RNA 5'-triphosphatase (RTPase) and RNA helicase activities and probably participates in transcription of the viral genome. Helicase activity might be involved in unwinding or reannealing dsRNA during RNA synthesis. RTPase enzymatic activity represents the first step in RNA capping, which yields a 5'-diphosphorylated plus-strand RNA.
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[[https://www.uniprot.org/uniprot/LMBD2_REOVD LMBD2_REOVD]] Outer capsid protein involved in mRNA capping. Catalyzes the last 3 enzymatic activities for formation of the 5' cap structure on the viral plus-strand transcripts, namely the RNA guanylyltransferase, RNA-7N- and RNA-2'O-methyltransferase activities. [[https://www.uniprot.org/uniprot/SIGM2_REOVD SIGM2_REOVD]] Inner capsid (core) component. [[https://www.uniprot.org/uniprot/LMBD1_REOVD LMBD1_REOVD]] Inner capsid (core) component. Displays NTPase, RNA 5'-triphosphatase (RTPase) and RNA helicase activities and probably participates in transcription of the viral genome. Helicase activity might be involved in unwinding or reannealing dsRNA during RNA synthesis. RTPase enzymatic activity represents the first step in RNA capping, which yields a 5'-diphosphorylated plus-strand RNA.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1ej6" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1ej6" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>

Revision as of 10:14, 12 January 2022

Reovirus core

1ej6, resolution 3.60Å

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