1pdi

From Proteopedia

(Difference between revisions)

Revision as of 10:17, 12 January 2022

Fitting of the C-terminal part of the short tail fibers into the cryo-EM reconstruction of T4 baseplate

1pdi, resolution 12.00Å

Structural highlights

1pdi is a 18 chain structure with sequence from Enterobacteria phage t4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Related:	1h6w, 1ocy
Experimental data:	Check to display Experimental Data
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[VG12_BPT4] Structural component of the short tail fiber. Secondary adhesin that binds irreversibly to the lipopolysaccharides component on the cell surface of Escherichia coli B strains during virus attachment.

Evolutionary Conservation

Checkto colour the structure by Evolutionary Conservation, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The baseplate of bacteriophage T4 is a multiprotein molecular machine that controls host cell recognition, attachment, tail sheath contraction and viral DNA ejection. We report here the three-dimensional structure of the baseplate-tail tube complex determined to a resolution of 12 A by cryoelectron microscopy. The baseplate has a six-fold symmetric, dome-like structure approximately 520 A in diameter and approximately 270 A long, assembled around a central hub. A 940 A-long and 96 A-diameter tail tube, coaxial with the hub, is connected to the top of the baseplate. At the center of the dome is a needle-like structure that was previously identified as a cell puncturing device. We have identified the locations of six proteins with known atomic structures, and established the position and shape of several other baseplate proteins. The baseplate structure suggests a mechanism of baseplate triggering and structural transition during the initial stages of T4 infection.

Three-dimensional structure of bacteriophage T4 baseplate.,Kostyuchenko VA, Leiman PG, Chipman PR, Kanamaru S, van Raaij MJ, Arisaka F, Mesyanzhinov VV, Rossmann MG Nat Struct Biol. 2003 Sep;10(9):688-93. Epub 2003 Aug 17. PMID:12923574^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Kostyuchenko VA, Leiman PG, Chipman PR, Kanamaru S, van Raaij MJ, Arisaka F, Mesyanzhinov VV, Rossmann MG. Three-dimensional structure of bacteriophage T4 baseplate. Nat Struct Biol. 2003 Sep;10(9):688-93. Epub 2003 Aug 17. PMID:12923574 doi:http://dx.doi.org/10.1038/nsb970

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1pdi"

@@ Line 3: / Line 3: @@
 <SX load='1pdi' size='340' side='right' viewer='molstar' caption='[[1pdi]], [[Resolution|resolution]] 12.00&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1pdi]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PDI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1PDI FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1pdi]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PDI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PDI FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1h6w|1h6w]], [[1ocy|1ocy]]</td></tr>
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1h6w|1h6w]], [[1ocy|1ocy]]</div></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1pdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pdi OCA], [http://pdbe.org/1pdi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1pdi RCSB], [http://www.ebi.ac.uk/pdbsum/1pdi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1pdi ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pdi OCA], [https://pdbe.org/1pdi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pdi RCSB], [https://www.ebi.ac.uk/pdbsum/1pdi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pdi ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/VG12_BPT4 VG12_BPT4]] Structural component of the short tail fiber. Secondary adhesin that binds irreversibly to the lipopolysaccharides component on the cell surface of Escherichia coli B strains during virus attachment.
+[[https://www.uniprot.org/uniprot/VG12_BPT4 VG12_BPT4]] Structural component of the short tail fiber. Secondary adhesin that binds irreversibly to the lipopolysaccharides component on the cell surface of Escherichia coli B strains during virus attachment.
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]

1pdi

From Proteopedia

Revision as of 10:17, 12 January 2022

Fitting of the C-terminal part of the short tail fibers into the cryo-EM reconstruction of T4 baseplate

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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