2jp6
From Proteopedia
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<StructureSection load='2jp6' size='340' side='right'caption='[[2jp6]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''> | <StructureSection load='2jp6' size='340' side='right'caption='[[2jp6]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2jp6]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JP6 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[2jp6]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JP6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JP6 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jp6 OCA], [https://pdbe.org/2jp6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jp6 RCSB], [https://www.ebi.ac.uk/pdbsum/2jp6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jp6 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/KA181_TITOB KA181_TITOB]] Reversible blocker of both Kv1.3/KCNA3 potassium channels (high affinity) and Shaker B (mammalian Kv1.1 analog) potassium channels (very low affinity).<ref>PMID:12445473</ref> |
==See Also== | ==See Also== | ||
Revision as of 08:15, 19 January 2022
Structural and functional characterization of the recombinant form of the Kv1.3 channel blocker Tc32
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