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3bpq

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==Crystal Structure of RelB-RelE antitoxin-toxin complex from Methanococcus jannaschii==
==Crystal Structure of RelB-RelE antitoxin-toxin complex from Methanococcus jannaschii==
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<StructureSection load='3bpq' size='340' side='right' caption='[[3bpq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='3bpq' size='340' side='right'caption='[[3bpq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3bpq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BPQ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3bpq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BPQ FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">relB3, relB, MJ1103.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA]), MJ1103, relE, relE3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">relB3, relB, MJ1103.1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA]), MJ1103, relE, relE3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bpq OCA], [http://pdbe.org/3bpq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3bpq RCSB], [http://www.ebi.ac.uk/pdbsum/3bpq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3bpq ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bpq OCA], [https://pdbe.org/3bpq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bpq RCSB], [https://www.ebi.ac.uk/pdbsum/3bpq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bpq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RELB3_METJA RELB3_METJA]] Antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the toxic activity of cognate toxin RelE (By similarity).<ref>PMID:15718296</ref> [[http://www.uniprot.org/uniprot/RELE3_METJA RELE3_METJA]] Toxic component of a toxin-antitoxin (TA) module. Has RNase activity (By similarity). Is very toxic upon expression in E.coli. Its toxic activity is probably neutralized by the cognate antitoxin RelB3.<ref>PMID:15718296</ref>
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[[https://www.uniprot.org/uniprot/RELB3_METJA RELB3_METJA]] Antitoxin component of a toxin-antitoxin (TA) module. Probably neutralizes the toxic activity of cognate toxin RelE (By similarity).<ref>PMID:15718296</ref> [[https://www.uniprot.org/uniprot/RELE3_METJA RELE3_METJA]] Toxic component of a toxin-antitoxin (TA) module. Has RNase activity (By similarity). Is very toxic upon expression in E.coli. Its toxic activity is probably neutralized by the cognate antitoxin RelB3.<ref>PMID:15718296</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bp/3bpq_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bp/3bpq_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Metja]]
[[Category: Metja]]
[[Category: Francuski, D]]
[[Category: Francuski, D]]

Revision as of 08:21, 19 January 2022

Crystal Structure of RelB-RelE antitoxin-toxin complex from Methanococcus jannaschii

PDB ID 3bpq

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