3btn
From Proteopedia
(Difference between revisions)
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==Crystal structure of antizyme inhibitor, an ornithine decarboxylase homologous protein== | ==Crystal structure of antizyme inhibitor, an ornithine decarboxylase homologous protein== | ||
- | <StructureSection load='3btn' size='340' side='right' caption='[[3btn]], [[Resolution|resolution]] 2.05Å' scene=''> | + | <StructureSection load='3btn' size='340' side='right'caption='[[3btn]], [[Resolution|resolution]] 2.05Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3btn]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3btn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BTN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BTN FirstGlance]. <br> |
- | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[7odc|7odc]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7odc|7odc]]</div></td></tr> |
- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Azin1, Oazi, Oazin ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Azin1, Oazi, Oazin ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3btn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3btn OCA], [https://pdbe.org/3btn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3btn RCSB], [https://www.ebi.ac.uk/pdbsum/3btn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3btn ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/AZIN1_MOUSE AZIN1_MOUSE]] Inhibits antizyme-dependent ODC degradation by binding to antizyme with greater affinity. Regulates cellular polyamine homeostasis.<ref>PMID:10698696</ref> <ref>PMID:18369191</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Antizyme Inhibitor|Antizyme Inhibitor]] | *[[Antizyme Inhibitor|Antizyme Inhibitor]] | ||
+ | *[[Antizyme inhibitor 3D structures|Antizyme inhibitor 3D structures]] | ||
*[[Ornithine decarboxylase|Ornithine decarboxylase]] | *[[Ornithine decarboxylase|Ornithine decarboxylase]] | ||
== References == | == References == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
[[Category: Lk3 transgenic mice]] | [[Category: Lk3 transgenic mice]] | ||
[[Category: Albeck, S]] | [[Category: Albeck, S]] |
Revision as of 08:24, 19 January 2022
Crystal structure of antizyme inhibitor, an ornithine decarboxylase homologous protein
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