3btn

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==Crystal structure of antizyme inhibitor, an ornithine decarboxylase homologous protein==
==Crystal structure of antizyme inhibitor, an ornithine decarboxylase homologous protein==
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<StructureSection load='3btn' size='340' side='right' caption='[[3btn]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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<StructureSection load='3btn' size='340' side='right'caption='[[3btn]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3btn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BTN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BTN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3btn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BTN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BTN FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[7odc|7odc]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[7odc|7odc]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Azin1, Oazi, Oazin ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Azin1, Oazi, Oazin ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3btn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3btn OCA], [http://pdbe.org/3btn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3btn RCSB], [http://www.ebi.ac.uk/pdbsum/3btn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3btn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3btn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3btn OCA], [https://pdbe.org/3btn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3btn RCSB], [https://www.ebi.ac.uk/pdbsum/3btn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3btn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AZIN1_MOUSE AZIN1_MOUSE]] Inhibits antizyme-dependent ODC degradation by binding to antizyme with greater affinity. Regulates cellular polyamine homeostasis.<ref>PMID:10698696</ref> <ref>PMID:18369191</ref>
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[[https://www.uniprot.org/uniprot/AZIN1_MOUSE AZIN1_MOUSE]] Inhibits antizyme-dependent ODC degradation by binding to antizyme with greater affinity. Regulates cellular polyamine homeostasis.<ref>PMID:10698696</ref> <ref>PMID:18369191</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Antizyme Inhibitor|Antizyme Inhibitor]]
*[[Antizyme Inhibitor|Antizyme Inhibitor]]
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*[[Antizyme inhibitor 3D structures|Antizyme inhibitor 3D structures]]
*[[Ornithine decarboxylase|Ornithine decarboxylase]]
*[[Ornithine decarboxylase|Ornithine decarboxylase]]
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Lk3 transgenic mice]]
[[Category: Albeck, S]]
[[Category: Albeck, S]]

Revision as of 08:24, 19 January 2022

Crystal structure of antizyme inhibitor, an ornithine decarboxylase homologous protein

PDB ID 3btn

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