Pyrroline-5-carboxylate reductase
From Proteopedia
(Difference between revisions)
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*Pyrroline-5-carboxylate reductase | *Pyrroline-5-carboxylate reductase | ||
| - | **[[2ger]] - | + | **[[2ger]] - hPYCR1 – human<BR /> |
| + | **[[6lhm]] – hPYCR2 <BR /> | ||
**[[5bse]] - bmPYCR - barrel medic<br /> | **[[5bse]] - bmPYCR - barrel medic<br /> | ||
**[[1yqg]] - NmPYCR – ''Neisseria meningitidis'' <BR /> | **[[1yqg]] - NmPYCR – ''Neisseria meningitidis'' <BR /> | ||
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*Pyrroline-5-carboxylate reductase complex | *Pyrroline-5-carboxylate reductase complex | ||
| - | **[[2izz]] - | + | **[[2izz]] - hPYCR1 + NAD <br /> |
| - | **[[2gra]], [[5uat]], [[5uaw]], [[5uax]] - | + | **[[2gra]], [[5uat]], [[5uaw]], [[5uax]] - hPYCR1 + NADP<br /> |
| - | **[[2gr9]] - | + | **[[2gr9]] - hPYCR1 + glutamate + NAD<br /> |
| - | **[[5uau]] - | + | **[[5uau]], [[6xp0]] - hPYCR1 + proline derivative<br /> |
| - | **[[5uav]] - | + | **[[6xp3]] – hPYCR1 + carboxylic acid<br /> |
| + | **[[6xoz]], [[6xp1]], [[6xp2]] – hPYCR1 + inhibitor<br /> | ||
| + | **[[5uav]] - hPYCR1 + tetrahydrofuroic acid + NADP<br /> | ||
**[[5bsf]] - bmPYCR + NAD<br /> | **[[5bsf]] - bmPYCR + NAD<br /> | ||
**[[5bsg]] - bmPYCR + NADP<br /> | **[[5bsg]] - bmPYCR + NADP<br /> | ||
Revision as of 07:46, 9 February 2022
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3D structures of pyrroline-5-carboxylate reductase
09-February-2022
References
- ↑ Giberti S, Funck D, Forlani G. Delta1-Pyrroline-5-carboxylate reductase from Arabidopsis thaliana: stimulation or inhibition by chloride ions and feedback regulation by proline depend on whether NADPH or NADH acts as co-substrate. New Phytol. 2014 May;202(3):911-9. doi: 10.1111/nph.12701. Epub 2014 Jan 28. PMID:24467670 doi:http://dx.doi.org/10.1111/nph.12701
- ↑ Nakayama T, Al-Maawali A, El-Quessny M, Rajab A, Khalil S, Stoler JM, Tan WH, Nasir R, Schmitz-Abe K, Hill RS, Partlow JN, Al-Saffar M, Servattalab S, LaCoursiere CM, Tambunan DE, Coulter ME, Elhosary PC, Gorski G, Barkovich AJ, Markianos K, Poduri A, Mochida GH. Mutations in PYCR2, Encoding Pyrroline-5-Carboxylate Reductase 2, Cause Microcephaly and Hypomyelination. Am J Hum Genet. 2015 May 7;96(5):709-19. doi: 10.1016/j.ajhg.2015.03.003. Epub, 2015 Apr 9. PMID:25865492 doi:http://dx.doi.org/10.1016/j.ajhg.2015.03.003
- ↑ Meng Z, Lou Z, Liu Z, Li M, Zhao X, Bartlam M, Rao Z. Crystal structure of human pyrroline-5-carboxylate reductase. J Mol Biol. 2006 Jun 23;359(5):1364-77. Epub 2006 May 11. PMID:16730026 doi:10.1016/j.jmb.2006.04.053
