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3dl2
From Proteopedia
(Difference between revisions)
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==Hexagonal structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A== | ==Hexagonal structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A== | ||
| - | <StructureSection load='3dl2' size='340' side='right' caption='[[3dl2]], [[Resolution|resolution]] 2.10Å' scene=''> | + | <StructureSection load='3dl2' size='340' side='right'caption='[[3dl2]], [[Resolution|resolution]] 2.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3dl2]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3dl2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DL2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DL2 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2i6t|2i6t]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2i6t|2i6t]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UEVLD, UEV3 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UEVLD, UEV3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dl2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dl2 OCA], [https://pdbe.org/3dl2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dl2 RCSB], [https://www.ebi.ac.uk/pdbsum/3dl2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dl2 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/UEVLD_HUMAN UEVLD_HUMAN]] Possible negative regulator of polyubiquitination.<ref>PMID:12427560</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Avvakumov, G V]] | [[Category: Avvakumov, G V]] | ||
Revision as of 08:01, 9 February 2022
Hexagonal structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A
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Categories: Human | Large Structures | Arrowsmith, C H | Avvakumov, G V | Bochkarev, A | Bountra, C | Butler-Cole, C | Dhe-Paganon, S | Edwards, A M | Finerty, P J | Newman, E M | Structural genomic | Walker, J R | Wolkstrom, M | Xue, S | Alternative splicing | L-lactate dehydrogenase | Nad | Oxidoreductase | Sgc | Ubiquitin-protein ligase | Ubl conjugation pathway | Unknown function

