SARS-CoV-2 protein NSP4
From Proteopedia
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== Function == | == Function == | ||
'''Non-structural protein 4 (nsp4)''' | '''Non-structural protein 4 (nsp4)''' | ||
| - | Participates in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication | + | Participates in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication<ref>[https://zhanglab.ccmb.med.umich.edu/COVID-19/ Modeling of the SARS-COV-2 Genome]</ref><ref>pmid 32200634</ref>. |
It helps build fluid-filled bubbles within infected cells. Inside these bubbles, parts for new copies of the virus are constructed<ref name="NY Times COVID-19">[https://www.nytimes.com/interactive/2020/04/03/science/coronavirus-genome-bad-news-wrapped-in-protein.html ''NY Times'' (3-Apr-2020) Bad News Wrapped in Protein: Inside the Coronavirus Genome]</ref>. | It helps build fluid-filled bubbles within infected cells. Inside these bubbles, parts for new copies of the virus are constructed<ref name="NY Times COVID-19">[https://www.nytimes.com/interactive/2020/04/03/science/coronavirus-genome-bad-news-wrapped-in-protein.html ''NY Times'' (3-Apr-2020) Bad News Wrapped in Protein: Inside the Coronavirus Genome]</ref>. | ||
Revision as of 13:47, 14 February 2022
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References
- ↑ 1.0 1.1 MIT ColabFold
- ↑ Modeling of the SARS-COV-2 Genome
- ↑ Zhang C, Zheng W, Huang X, Bell EW, Zhou X, Zhang Y. Protein Structure and Sequence Reanalysis of 2019-nCoV Genome Refutes Snakes as Its Intermediate Host and the Unique Similarity between Its Spike Protein Insertions and HIV-1. J Proteome Res. 2020 Apr 3;19(4):1351-1360. doi: 10.1021/acs.jproteome.0c00129., Epub 2020 Mar 24. PMID:32200634 doi:http://dx.doi.org/10.1021/acs.jproteome.0c00129
- ↑ NY Times (3-Apr-2020) Bad News Wrapped in Protein: Inside the Coronavirus Genome
