1gd6

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[[Image:1gd6.gif|left|200px]]
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{{Structure
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gd6 OCA], [http://www.ebi.ac.uk/pdbsum/1gd6 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1gd6 RCSB]</span>
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'''STRUCTURE OF THE BOMBYX MORI LYSOZYME'''
'''STRUCTURE OF THE BOMBYX MORI LYSOZYME'''
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[[Category: Yao, M.]]
[[Category: Yao, M.]]
[[Category: 1,4-beta-n-acetylmuramidase]]
[[Category: 1,4-beta-n-acetylmuramidase]]
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[[Category: bmlz]]
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[[Category: Bmlz]]
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[[Category: lysozyme]]
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[[Category: Lysozyme]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 17:26:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:41:44 2008''
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Revision as of 14:26, 2 May 2008

Image:1gd6.gif

Template:STRUCTURE 1gd6

STRUCTURE OF THE BOMBYX MORI LYSOZYME


Overview

Bombyx mori lysozyme (BmLZ), from the silkworm, is an insect lysozyme. BmLZ has considerable activity at low temperatures and low activation energies compared with those of hen egg white lysozyme (HEWLZ), according to measurements of the temperature dependencies of relative activity (lytic and glycol chitin) and the estimation of activation energies using the Arrhenius equation. Being so active at low temperatures and low activation energies is characteristic of psychrophilic (cold-adapted) enzymes. The three-dimensional structure of BmLZ has been determined by X-ray crystallography at 2.5 A resolution. The core structure of BmLZ is similar to that of c-type lysozymes. However, BmLZ shows some distinct differences in the two exposed loops and the C-terminal region. A detailed comparison of BmLZ and HEWLZ suggests structural rationalizations for the differences in the catalytic efficiency, stability, and mode of activity between these two lysozymes.

About this Structure

1GD6 is a Single protein structure of sequence from Bombyx mori. Full crystallographic information is available from OCA.

Reference

Structural analysis of an insect lysozyme exhibiting catalytic efficiency at low temperatures., Matsuura A, Yao M, Aizawa T, Koganesawa N, Masaki K, Miyazawa M, Demura M, Tanaka I, Kawano K, Nitta K, Biochemistry. 2002 Oct 8;41(40):12086-92. PMID:12356308 Page seeded by OCA on Fri May 2 17:26:03 2008

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