This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7f8n
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Human pannexin-1 showing a conformational change in the N-terminal domain and blocked pore== | ==Human pannexin-1 showing a conformational change in the N-terminal domain and blocked pore== | ||
| - | <StructureSection load='7f8n' size='340' side='right'caption='[[7f8n]]' scene=''> | + | <StructureSection load='7f8n' size='340' side='right'caption='[[7f8n]], [[Resolution|resolution]] 3.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7F8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7F8N FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7f8n]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7F8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7F8N FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7f8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7f8n OCA], [https://pdbe.org/7f8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7f8n RCSB], [https://www.ebi.ac.uk/pdbsum/7f8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7f8n ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LBN:1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine'>LBN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7f8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7f8n OCA], [https://pdbe.org/7f8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7f8n RCSB], [https://www.ebi.ac.uk/pdbsum/7f8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7f8n ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/PANX1_HUMAN PANX1_HUMAN]] Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.<ref>PMID:16908669</ref> <ref>PMID:20829356</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Fujiyoshi Y]] | + | [[Category: Fujiyoshi, Y]] |
| - | [[Category: Hayashida K]] | + | [[Category: Hayashida, K]] |
| - | [[Category: Hirano H]] | + | [[Category: Hirano, H]] |
| - | [[Category: Kobayashi K]] | + | [[Category: Kobayashi, K]] |
| - | [[Category: Kuzuya M]] | + | [[Category: Kuzuya, M]] |
| - | [[Category: Oshima A]] | + | [[Category: Oshima, A]] |
| - | [[Category: Tani K]] | + | [[Category: Tani, K]] |
| - | [[Category: Watanabe M]] | + | [[Category: Watanabe, M]] |
| + | [[Category: Atp release channel]] | ||
| + | [[Category: Transport protein]] | ||
| + | [[Category: Vertebrate innexin homolog]] | ||
Revision as of 10:59, 16 February 2022
Human pannexin-1 showing a conformational change in the N-terminal domain and blocked pore
| |||||||||||
