7f8n
From Proteopedia
(Difference between revisions)
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==Human pannexin-1 showing a conformational change in the N-terminal domain and blocked pore== | ==Human pannexin-1 showing a conformational change in the N-terminal domain and blocked pore== | ||
| - | <StructureSection load='7f8n' size='340' side='right'caption='[[7f8n]]' scene=''> | + | <StructureSection load='7f8n' size='340' side='right'caption='[[7f8n]], [[Resolution|resolution]] 3.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7F8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7F8N FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7f8n]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7F8N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7F8N FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7f8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7f8n OCA], [https://pdbe.org/7f8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7f8n RCSB], [https://www.ebi.ac.uk/pdbsum/7f8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7f8n ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LBN:1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine'>LBN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7f8n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7f8n OCA], [https://pdbe.org/7f8n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7f8n RCSB], [https://www.ebi.ac.uk/pdbsum/7f8n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7f8n ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/PANX1_HUMAN PANX1_HUMAN]] Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.<ref>PMID:16908669</ref> <ref>PMID:20829356</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Fujiyoshi Y]] | + | [[Category: Fujiyoshi, Y]] |
| - | [[Category: Hayashida K]] | + | [[Category: Hayashida, K]] |
| - | [[Category: Hirano H]] | + | [[Category: Hirano, H]] |
| - | [[Category: Kobayashi K]] | + | [[Category: Kobayashi, K]] |
| - | [[Category: Kuzuya M]] | + | [[Category: Kuzuya, M]] |
| - | [[Category: Oshima A]] | + | [[Category: Oshima, A]] |
| - | [[Category: Tani K]] | + | [[Category: Tani, K]] |
| - | [[Category: Watanabe M]] | + | [[Category: Watanabe, M]] |
| + | [[Category: Atp release channel]] | ||
| + | [[Category: Transport protein]] | ||
| + | [[Category: Vertebrate innexin homolog]] | ||
Revision as of 10:59, 16 February 2022
Human pannexin-1 showing a conformational change in the N-terminal domain and blocked pore
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