1k0s

From Proteopedia

(Difference between revisions)

Revision as of 08:06, 23 February 2022

Solution structure of the chemotaxis protein CheW from the thermophilic organism Thermotoga maritima

Structural highlights

1k0s is a 1 chain structure with sequence from Atcc 43589. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:	CheW (ATCC 43589)
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[CHEW_THEMA] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Using protein from the hyperthermophile Thermotoga maritima, we have determined the solution structure of CheW, an essential component in the formation of the bacterial chemotaxis signaling complex. The overall fold is similar to the regulatory domain of the chemotaxis kinase CheA. In addition, interactions of CheW with CheA were monitored by nuclear magnetic resonance (NMR) techniques. The chemical shift perturbation data show the probable contacts that CheW makes with CheA. In combination with previous genetic data, the structure also suggests a possible binding site for the chemotaxis receptor. These results provide a structural basis for a model in which CheW acts as a molecular bridge between CheA and the cytoplasmic tails of the receptor.

The solution structure and interactions of CheW from Thermotoga maritima.,Griswold IJ, Zhou H, Matison M, Swanson RV, McIntosh LP, Simon MI, Dahlquist FW Nat Struct Biol. 2002 Feb;9(2):121-5. PMID:11799399^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Griswold IJ, Zhou H, Matison M, Swanson RV, McIntosh LP, Simon MI, Dahlquist FW. The solution structure and interactions of CheW from Thermotoga maritima. Nat Struct Biol. 2002 Feb;9(2):121-5. PMID:11799399 doi:10.1038/nsb753

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 See Also
6 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1k0s"

@@ Line 3: / Line 3: @@
 <StructureSection load='1k0s' size='340' side='right'caption='[[1k0s]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1k0s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0S OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1K0S FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1k0s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K0S FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CheW ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr>
+</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CheW ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 ATCC 43589])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1k0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k0s OCA], [http://pdbe.org/1k0s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1k0s RCSB], [http://www.ebi.ac.uk/pdbsum/1k0s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1k0s ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k0s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k0s OCA], [https://pdbe.org/1k0s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k0s RCSB], [https://www.ebi.ac.uk/pdbsum/1k0s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k0s ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/CHEW_THEMA CHEW_THEMA]] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors (By similarity).
+[[https://www.uniprot.org/uniprot/CHEW_THEMA CHEW_THEMA]] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors (By similarity).
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]

1k0s

From Proteopedia

Revision as of 08:06, 23 February 2022

Solution structure of the chemotaxis protein CheW from the thermophilic organism Thermotoga maritima

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

See Also

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

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