6zzr
From Proteopedia
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| - | ==The Crystal Structure of human LDHA from | + | ==The Crystal Structure of human LDHA from Biortus== |
| - | <StructureSection load='6zzr' size='340' side='right'caption='[[6zzr]]' scene=''> | + | <StructureSection load='6zzr' size='340' side='right'caption='[[6zzr]], [[Resolution|resolution]] 2.65Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZZR OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6zzr]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZZR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZZR FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LDHA, PIG19 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zzr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zzr OCA], [https://pdbe.org/6zzr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zzr RCSB], [https://www.ebi.ac.uk/pdbsum/6zzr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zzr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [[https://www.uniprot.org/uniprot/LDHA_HUMAN LDHA_HUMAN]] Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:[https://omim.org/entry/612933 612933]]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.<ref>PMID:2334430</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: L-lactate dehydrogenase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bao X]] | + | [[Category: Bao, X]] |
| - | [[Category: Cheng W]] | + | [[Category: Cheng, W]] |
| - | [[Category: Lin D]] | + | [[Category: Lin, D]] |
| - | [[Category: Shang H]] | + | [[Category: Shang, H]] |
| - | [[Category: Wang F]] | + | [[Category: Wang, F]] |
| - | [[Category: Zhu B]] | + | [[Category: Zhu, B]] |
| + | [[Category: Cadherin binding]] | ||
| + | [[Category: L-lactate dehydrogenase activity]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 08:32, 23 February 2022
The Crystal Structure of human LDHA from Biortus
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