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3epn

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<StructureSection load='3epn' size='340' side='right'caption='[[3epn]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
<StructureSection load='3epn' size='340' side='right'caption='[[3epn]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3epn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EPN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3EPN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3epn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EPN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EPN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IRN:1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE'>IRN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IRN:1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE'>IRN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3epm|3epm]], [[3epo|3epo]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3epm|3epm]], [[3epo|3epo]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3epn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3epn OCA], [http://pdbe.org/3epn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3epn RCSB], [http://www.ebi.ac.uk/pdbsum/3epn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3epn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3epn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3epn OCA], [https://pdbe.org/3epn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3epn RCSB], [https://www.ebi.ac.uk/pdbsum/3epn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3epn ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/THIC_CAUCR THIC_CAUCR]] Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<ref>PMID:18953358</ref>
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[[https://www.uniprot.org/uniprot/THIC_CAUCR THIC_CAUCR]] Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<ref>PMID:18953358</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 09:12, 23 February 2022

Crystal structure of Caulobacter crescentus ThiC complexed with imidazole ribonucleotide

PDB ID 3epn

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