User:Andrew Peters/Sandbox 1

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Current revision (21:15, 1 March 2022) (edit) (undo)
 
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=ALK H. sapiens=
=ALK H. sapiens=
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<StructureSection load='7LS0' size='350' frame='true' side='right' caption='ALK 7LS0' scene=’<scene name='90/905625/First_alk/3'>TextToBeDisplayed</scene>’>
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<StructureSection load='7LS0' size='350' frame='true' side='right' caption='ALK 7LS0'>
==Introduction==
==Introduction==
[[Image:Mutated F856S.png|400 px|right|thumb|Figure 1]]
[[Image:Mutated F856S.png|400 px|right|thumb|Figure 1]]
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=== Conformation Change ===
=== Conformation Change ===
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<scene name='90/905625/White_alk/1'>domains of possible mutations</scene>
== Disease ==
== Disease ==
[https://www.alecensa.com/patient/what-is-alk-positive-mnsclc/what-is-alk-positive-mnsclc.html?c=ale-1675b87a1d3&gclid=EAIaIQobChMIzt7rreCl9gIVlxmtBh04iQLQEAAYASABEgJFsPD_BwE&gclsrc=aw.ds NSCLC]
[https://www.alecensa.com/patient/what-is-alk-positive-mnsclc/what-is-alk-positive-mnsclc.html?c=ale-1675b87a1d3&gclid=EAIaIQobChMIzt7rreCl9gIVlxmtBh04iQLQEAAYASABEgJFsPD_BwE&gclsrc=aw.ds NSCLC]
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enter <ref name=”Du”>PMID:29488330</ref>
=== Cancer ===
=== Cancer ===
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<ref name="Ransey">PMID:28504306</ref>
== Relevance ==
== Relevance ==
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<ref name="Ransey" />
== Structural highlights ==
== Structural highlights ==

Current revision

ALK H. sapiens

ALK 7LS0

Drag the structure with the mouse to rotate

References

  1. Du X, Shao Y, Qin HF, Tai YH, Gao HJ. ALK-rearrangement in non-small-cell lung cancer (NSCLC). Thorac Cancer. 2018 Apr;9(4):423-430. doi: 10.1111/1759-7714.12613. Epub 2018 Feb, 28. PMID:29488330 doi:http://dx.doi.org/10.1111/1759-7714.12613
  2. 2.0 2.1 Ransey E, Paredes E, Dey SK, Das SR, Heroux A, Macbeth MR. Crystal structure of the Entamoeba histolytica RNA lariat debranching enzyme EhDbr1 reveals a catalytic Zn(2+) /Mn(2+) heterobinucleation. FEBS Lett. 2017 Jul;591(13):2003-2010. doi: 10.1002/1873-3468.12677. Epub 2017, Jun 14. PMID:28504306 doi:http://dx.doi.org/10.1002/1873-3468.12677

Student Contributors

  • Drew Peters

Proteopedia Page Contributors and Editors (what is this?)

Andrew Peters

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