1x4b

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<StructureSection load='1x4b' size='340' side='right'caption='[[1x4b]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1x4b' size='340' side='right'caption='[[1x4b]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1x4b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X4B OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1X4B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1x4b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X4B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X4B FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNRPA2B1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HNRPA2B1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1x4b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x4b OCA], [http://pdbe.org/1x4b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1x4b RCSB], [http://www.ebi.ac.uk/pdbsum/1x4b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1x4b ProSAT], [http://www.topsan.org/Proteins/RSGI/1x4b TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x4b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x4b OCA], [https://pdbe.org/1x4b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x4b RCSB], [https://www.ebi.ac.uk/pdbsum/1x4b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x4b ProSAT], [https://www.topsan.org/Proteins/RSGI/1x4b TOPSAN]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[http://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN]] Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>
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[[https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN]] Inclusion body myopathy with Paget disease of bone and frontotemporal dementia. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:23455423</ref>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN]] Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus.
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[[https://www.uniprot.org/uniprot/ROA2_HUMAN ROA2_HUMAN]] Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 07:03, 2 March 2022

Solution structure of RRM domain in Heterogeneous nuclear ribonucleaoproteins A2/B1

PDB ID 1x4b

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