1x58
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='1x58' size='340' side='right'caption='[[1x58]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='1x58' size='340' side='right'caption='[[1x58]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1x58]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1x58]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X58 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X58 FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">4930532D21Rik ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">4930532D21Rik ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x58 OCA], [https://pdbe.org/1x58 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x58 RCSB], [https://www.ebi.ac.uk/pdbsum/1x58 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x58 ProSAT], [https://www.topsan.org/Proteins/RSGI/1x58 TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/TERB1_MOUSE TERB1_MOUSE]] Meiosis-specific telomere-associated protein involved in meiotic telomere clustering, also named bouquet formation, the telomere-mediated chromosomal movement along the nuclear envelope which is crucial for homologous pairing and synapsis. Probably acts as a hub for the assembly of a conserved meiotic telomere complex required for chromosome movements via interaction with TERF1. Promotes telomere association with the nuclear envelope and deposition of the SUN-KASH/LINC complex. Also recruits cohesin to telomeres to develop structural rigidity.<ref>PMID:24413433</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:05, 2 March 2022
Solution structures of the myb-like DNA binding domain of 4930532D21Rik protein
| |||||||||||
Categories: Large Structures | Lk3 transgenic mice | Inoue, M | Kigawa, T | Koshiba, S | Nameki, N | Structural genomic | Tomizawa, T | Yokoyama, S | Mus musculus adult male testis cdna | National project on protein structural and functional analyse | Nppsfa | Riken full-length enriched library | Rsgi | Unknown function
