3fhj
From Proteopedia
(Difference between revisions)
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<StructureSection load='3fhj' size='340' side='right'caption='[[3fhj]], [[Resolution|resolution]] 2.65Å' scene=''> | <StructureSection load='3fhj' size='340' side='right'caption='[[3fhj]], [[Resolution|resolution]] 2.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3fhj]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3fhj]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FHJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FHJ FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene></td></tr> |
- | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1d2r|1d2r]], [[1mb2|1mb2]], [[1m83|1m83]], [[2ov4|2ov4]], [[1i6k|1i6k]], [[3fi0|3fi0]], [[1mau|1mau]], [[1i6m|1i6m]], [[1i6l|1i6l]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1d2r|1d2r]], [[1mb2|1mb2]], [[1m83|1m83]], [[2ov4|2ov4]], [[1i6k|1i6k]], [[3fi0|3fi0]], [[1mau|1mau]], [[1i6m|1i6m]], [[1i6l|1i6l]]</div></td></tr> |
- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpS ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpS ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 ATCC 12980])</td></tr> |
- | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Tryptophan--tRNA_ligase Tryptophan--tRNA ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.2 6.1.1.2] </span></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fhj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fhj OCA], [https://pdbe.org/3fhj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fhj RCSB], [https://www.ebi.ac.uk/pdbsum/3fhj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fhj ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == |
Revision as of 08:01, 2 March 2022
Independent saturation of three TrpRS subsites generates a partially-assembled state similar to those observed in molecular simulations
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Categories: Atcc 12980 | Large Structures | Tryptophan--tRNA ligase | Carter, C W | Delarue, M | Kapustina, M | Koehl, P | Laowanapiban, P | Vonrhein, C | Aminoacyl-trna synthetase | Atp-binding | Cytoplasm | Ligand-dependent domain rearrangement | Ligase | Mechanistic pathway | Molecular simulation | Nucleotide-binding | Protein biosynthesis | Translation