Ribosome biogenesis protein
From Proteopedia
(Difference between revisions)
| Line 4: | Line 4: | ||
== Function == | == Function == | ||
| - | '''Ribosome biogenesis proteins''' are factors which contribute to the maturation of the ribosome. | + | '''Ribosome biogenesis proteins''' or '''ribosome assembly factor''' are factors which contribute to the maturation of the ribosome. |
'''Interactive 3D figure''' on right side shows: Ribosome biogenesis protein Nop10 (pink) complexed with pseudouridine synthase (grey), GAR1 (green), ribosomal protein L7AE (yellow), H/ACA RNA (magenta) and RNA containing pseudouridine (cyan) (PDB code [[3hay]]) | '''Interactive 3D figure''' on right side shows: Ribosome biogenesis protein Nop10 (pink) complexed with pseudouridine synthase (grey), GAR1 (green), ribosomal protein L7AE (yellow), H/ACA RNA (magenta) and RNA containing pseudouridine (cyan) (PDB code [[3hay]]) | ||
| Line 20: | Line 20: | ||
</StructureSection> | </StructureSection> | ||
== 3D Structures of ribosome biogenesis protein == | == 3D Structures of ribosome biogenesis protein == | ||
| - | + | [[Ribosome biogenesis protein 3D structures]] | |
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| Line 40: | Line 40: | ||
*Ribosome biogenesis protein complex | *Ribosome biogenesis protein complex | ||
| + | **[[7mq9]], [[7mqa]], [[7mqs]] – hRBP in processome SSU – Cryo EM<br /> | ||
**[[6g18]], [[6g4s]], [[6g4w]], [[6g51]], [[6g53]] – hTsr1 in 40S subunit – Cryo EM<br /> | **[[6g18]], [[6g4s]], [[6g4w]], [[6g51]], [[6g53]] – hTsr1 in 40S subunit – Cryo EM<br /> | ||
**[[6zmt]], [[6zn6]] – hTsr1 in 40S subunit + RACK1 + SARS non-structural protein – Cryo EM<br /> | **[[6zmt]], [[6zn6]] – hTsr1 in 40S subunit + RACK1 + SARS non-structural protein – Cryo EM<br /> | ||
| - | **[[ | + | **[[6lss]] – hRBP in pre-40S subunit – Cryo EM<br /> |
| + | **[[6lu8]] – hRBP in pre-60S subunit – Cryo EM<br /> | ||
| + | **[[6fai]], [[6wdr]], [[6y7c]], [[6rbd]] – yTsr1 + 40S ribosome - Cryo EM <br /> | ||
| + | **[[6c0f]], [[6cb1]], [[6elz]], [[6em1]], [[6em3]], [[6em4]], [[6em5]], [[6eml]], [[6m62]], [[6n8j]], [[6n8k]], [[6n8l]], [[7bt6]], [[7btb]] – yNsa1 in pre-60S subunit – Cryo EM<br /> | ||
| + | **[[7of1]], [[7oh3]], [[7ohp]], [[7ohq]], [[7ohr]], [[7ohs]], [[7oht]], [[7ohu]], [[7ohv]], [[7ohw]], [[7ohx]], [[7ohy]] – yNog1 in pre-60S subunit – Cryo EM<br /> | ||
| + | **[[6ft6]], [[6ylg]], [[6ylh]], [[6ylx]], [[6yly]] – yNop53 in pre-60S subunit – Cryo EM<br /> | ||
| + | **[[6ke6]], [[6lqp]], [[6lqq]], [[6lqr]], [[6lqs]], [[6lqt]], [[6lqu]], [[6lqv]], [[6zqa]], [[6zqb]], [[6zqc]], [[6zqd]], [[6zqe]], [[6zqf]], [[6zqg]], [[7d5s]] – yNsa1 in pre-90S subunit – Cryo EM<br /> | ||
| + | **[[7d5t]], [[7d63]] – yUtp24 in pre-90S subunit – Cryo EM<br /> | ||
| + | **[[7ajt]], [[7aju]] – yUtp24 in pre-90S subunit + exosome – Cryo EM<br /> | ||
| + | **[[7d4i]] – yRBP in 90S + RNA helicase – Cryo EM<br /> | ||
**[[5tzs]], [[5wyj]], [[5wyk]] – yBms1 + 40S ribosome - Cryo EM <br /> | **[[5tzs]], [[5wyj]], [[5wyk]] – yBms1 + 40S ribosome - Cryo EM <br /> | ||
**[[5wxl]], [[5a53]] – yRpf2 + regulator of ribosome biosynthesis <br /> | **[[5wxl]], [[5a53]] – yRpf2 + regulator of ribosome biosynthesis <br /> | ||
Revision as of 08:28, 2 March 2022
| |||||||||||
3D Structures of ribosome biogenesis protein
Ribosome biogenesis protein 3D structures Updated on 02-March-2022
References
- ↑ Marcin W, Neira JL, Bravo J. The Carboxy-Terminal Domain of Erb1 Is a Seven-Bladed ss-Propeller that Binds RNA. PLoS One. 2015 Apr 16;10(4):e0123463. doi: 10.1371/journal.pone.0123463., eCollection 2015. PMID:25880847 doi:http://dx.doi.org/10.1371/journal.pone.0123463
- ↑ Hamma T, Reichow SL, Varani G, Ferre-D'Amare AR. The Cbf5-Nop10 complex is a molecular bracket that organizes box H/ACA RNPs. Nat Struct Mol Biol. 2005 Dec;12(12):1101-7. Epub 2005 Nov 15. PMID:16286935 doi:10.1038/nsmb1036
- ↑ Hu J, Zhu X, Ye K. Structure and RNA recognition of ribosome assembly factor Utp30. RNA. 2017 Sep 26. pii: rna.062695.117. doi: 10.1261/rna.062695.117. PMID:28951391 doi:http://dx.doi.org/10.1261/rna.062695.117
- ↑ McCaughan UM, Jayachandran U, Shchepachev V, Chen ZA, Rappsilber J, Tollervey D, Cook AG. Pre-40S ribosome biogenesis factor Tsr1 is an inactive structural mimic of translational GTPases. Nat Commun. 2016 Jun 2;7:11789. doi: 10.1038/ncomms11789. PMID:27250689 doi:http://dx.doi.org/10.1038/ncomms11789
- ↑ Taylor AB, Meyer B, Leal BZ, Kotter P, Schirf V, Demeler B, Hart PJ, Entian KD, Wohnert J. The crystal structure of Nep1 reveals an extended SPOUT-class methyltransferase fold and a pre-organized SAM-binding site. Nucleic Acids Res. 2008 Mar;36(5):1542-54. Epub 2008 Jan 21. PMID:18208838 doi:10.1093/nar/gkm1172
- ↑ Delprato A, Al Kadri Y, Perebaskine N, Monfoulet C, Henry Y, Henras AK, Fribourg S. Crucial role of the Rcl1p-Bms1p interaction for yeast pre-ribosomal RNA processing. Nucleic Acids Res. 2014;42(15):10161-72. doi: 10.1093/nar/gku682. Epub 2014 Jul, 26. PMID:25064857 doi:http://dx.doi.org/10.1093/nar/gku682
- ↑ Liang B, Zhou J, Kahen E, Terns RM, Terns MP, Li H. Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA. Nat Struct Mol Biol. 2009 Jul;16(7):740-6. Epub 2009 May 28. PMID:19478803 doi:10.1038/nsmb.1624
