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Ribozyme

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</StructureSection>
</StructureSection>
== 3D Structures of Ribozymes ==
== 3D Structures of Ribozymes ==
 +
[[Ribozyme 3D structures]]
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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**[[1y0q]] – RZ group I + RNA – Staphylococcus phage twort<BR />
**[[1y0q]] – RZ group I + RNA – Staphylococcus phage twort<BR />
**[[1x8w]] – TtRZ – ''Tetrahymena thermophilia''<BR />
**[[1x8w]] – TtRZ – ''Tetrahymena thermophilia''<BR />
 +
**[[6wls]], [[7ez0]], [[7ez2]] – TtRZ – Cryo EM<br />
**[[1grz]], [[6bjx]], [[6d8l]], [[6d8m]], [[6d8n]], [[6d8o]] – TtRZ (mutant) <BR />
**[[1grz]], [[6bjx]], [[6d8l]], [[6d8m]], [[6d8n]], [[6d8o]] – TtRZ (mutant) <BR />
**[[1l8v]], [[1gid]] – TtRZ P4-P6 domain<BR />
**[[1l8v]], [[1gid]] – TtRZ P4-P6 domain<BR />
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**[[1ykq]] – Diels-Alder RZ<BR />
**[[1ykq]] – Diels-Alder RZ<BR />
**[[1ykv]], [[1yls]] - Diels-Alder RZ + reaction products<br />
**[[1ykv]], [[1yls]] - Diels-Alder RZ + reaction products<br />
-
**[[4qjh]], [[5dun]] – twister RZ – synthetic<br />
+
**[[4qjh]], [[5dun]] – twister sRZ – synthetic<br />
-
**[[4rge]], [[4rgf]] – twister RZ env22 – synthetic<br />
+
**[[4rge]], [[4rgf]] – twister sRZ env22 <br />
**[[5t5a]], [[5y85]], [[5y87]] – twister sister RZ – Metagenome<br />
**[[5t5a]], [[5y85]], [[5y87]] – twister sister RZ – Metagenome<br />
-
**[[5k7c]],[[5k7d]],[[5k7e]], [[5ktj]] - pistol RZ - synthetic <br/>
+
**[[5k7c]],[[5k7d]],[[5k7e]], [[5ktj]], [[6ufj]], [[6ufk]] - pistol sRZ <br/>
-
**[[6gyv]] – lariat-capping RZ – ''Didymium iridis''<BR />
+
**[[6uey]], [[6uf1]] – pistol EcRZ <br />
 +
**[[6r47]] – pistol RZ – Alistipes putredinis <br />
 +
**[[6g7z]], [[6gyv]] – lariat-capping RZ – ''Didymium iridis''<BR />
 +
**[[6jq5]], [[6jq6]] – hatchet sRZ <br />
 +
**[[6xjq]], [[6xjw]], [[6xjy]], [[6xjz]] – self-alkylating RZ + antibody – ''Aeropyrum pernix'' <br />
 +
**[[7dlz]], [[7dwh]] – SAM-dependent methyltransferase sRZ + U1A <br />
 +
**[[6wll]], [[6wlm]] – Gly RZ – ''Fusobacterium nucleatum'' <br />
 +
**[[6wlt]], [[6wlu]] – Gly RZ – ''Vibrio cholerae'' <br />
}}
}}

Revision as of 10:07, 3 March 2022

Hammerhead ribozyme, (PDB-ID 379d)

Drag the structure with the mouse to rotate

3D Structures of Ribozymes

Ribozyme 3D structures

Updated on 03-March-2022

References

  1. Tang J, Breaker RR. Rational design of allosteric ribozymes. Chem Biol. 1997 Jun;4(6):453-9. PMID:9224568
  2. Amarzguioui M, Prydz H. Hammerhead ribozyme design and application. Cell Mol Life Sci. 1998 Nov;54(11):1175-202. PMID:9849614 doi:http://dx.doi.org/10.1007/s000180050247
  3. Cech TR. Self-splicing of group I introns. Annu Rev Biochem. 1990;59:543-68. PMID:2197983 doi:http://dx.doi.org/10.1146/annurev.bi.59.070190.002551
  4. Roth A, Weinberg Z, Chen AG, Kim PB, Ames TD, Breaker RR. A widespread self-cleaving ribozyme class is revealed by bioinformatics. Nat Chem Biol. 2014 Jan;10(1):56-60. doi: 10.1038/nchembio.1386. Epub 2013 Nov, 17. PMID:24240507 doi:http://dx.doi.org/10.1038/nchembio.1386
  5. Weinberg Z, Kim PB, Chen TH, Li S, Harris KA, Lunse CE, Breaker RR. New classes of self-cleaving ribozymes revealed by comparative genomics analysis. Nat Chem Biol. 2015 Aug;11(8):606-10. doi: 10.1038/nchembio.1846. Epub 2015 Jul, 13. PMID:26167874 doi:http://dx.doi.org/10.1038/nchembio.1846

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