This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3fxp
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='3fxp' size='340' side='right'caption='[[3fxp]], [[Resolution|resolution]] 2.05Å' scene=''> | <StructureSection load='3fxp' size='340' side='right'caption='[[3fxp]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3fxp]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3fxp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FXP FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=D38:N~2~-[(2S)-2-{[1-(4-CARBOXYBENZYL)-1H-1,2,3-TRIAZOL-4-YL]METHYL}-3-METHYLBUTANOYL]-L-LYSINE'>D38</scene>, <scene name='pdbligand=GLO:D-GLUCOSE+IN+LINEAR+FORM'>GLO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=D38:N~2~-[(2S)-2-{[1-(4-CARBOXYBENZYL)-1H-1,2,3-TRIAZOL-4-YL]METHYL}-3-METHYLBUTANOYL]-L-LYSINE'>D38</scene>, <scene name='pdbligand=GLO:D-GLUCOSE+IN+LINEAR+FORM'>GLO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3eim|3eim]], [[3fcq|3fcq]], [[8tln|8tln]], [[3fxs|3fxs]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3eim|3eim]], [[3fcq|3fcq]], [[8tln|8tln]], [[3fxs|3fxs]]</div></td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fxp OCA], [https://pdbe.org/3fxp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fxp RCSB], [https://www.ebi.ac.uk/pdbsum/3fxp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fxp ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH]] Extracellular zinc metalloprotease. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 23: | Line 23: | ||
==See Also== | ==See Also== | ||
| - | *[[Thermolysin|Thermolysin]] | + | *[[Thermolysin 3D structures|Thermolysin 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 07:50, 9 March 2022
Thermolysin inhibition
| |||||||||||

