RNA uridylyltransferase

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*RNA uridylyltransferase-1
*RNA uridylyltransferase-1
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**[[2e5g]] – hRNAU-1 RNA recognition motif – human – NMR<br />
+
*RNA uridylyltransferase-1
-
**[[3pq1]] – hRNAU-1 (mutant)<br />
+
 
-
**[[6l3f]] – AtRNAU-1 (mutant) – ''Arabidopsis thaliana''<br />
+
**[[2e5g]] – hTUT-1 RNA recognition motif – human – NMR<br />
-
**[[6l8k]] – AtRNAU-1 + UTP<br />
+
**[[3pq1]] – hTUT-1 (mutant)<br />
 +
**[[6l3f]] – AtTUT-1 (mutant) – ''Arabidopsis thaliana''<br />
 +
**[[6l8k]] – AtTUT-1 + UTP<br />
 +
**[[2b51]], [[5hcd]] – TbTUT-1 – ''Trypanosoma brucei''<br />
 +
**[[5ido]] – TbTUT-1 + UTP <br />
 +
**[[5i49]] – TbTUT-1 + UMPNPP <br />
*RNA uridylyltransferase-4
*RNA uridylyltransferase-4
-
**[[2q0c]], [[2q0d]], [[2q0e]], [[2q0f]], [[2q0g]], [[2ikf]], [[2nom]], [[5kal]] – TbRNAU-4 + nucleotide – ''Trypanosoma brucei''<br />
+
**[[6iw6]] – hTUT-4 253-723<br />
 +
**[[2q0c]], [[2q0d]], [[2q0e]], [[2q0f]], [[2q0g]], [[2ikf]], [[2nom]], [[5kal]] – TbTUT-4 + nucleotide <br />
 +
 
 +
*RNA uridylyltransferase-7
 +
 
 +
**[[5w0b]] – hTUT-7 catalytic module<br />
 +
**[[5w0m]] – hTUT-7 + U5 ssRNA <br />
 +
**[[5w0o]] – hTUT-7 + dsRNA + UTPbr />
 +
**[[5w0n]] – hTUT-7 + U2 ssRNA + UMPNPP<br />
 +
 
 +
*TUTase Tailor
 +
 
 +
**[[5z4c]] – DmTUTT – ''Drosophila melanogaster'' <br />
 +
**[[5z4a]], [[5z4d]], [[5z4j]], [[6i0t]], [[6i0u]], [[6i0v]] – DmTUTT + RNA <br />
 +
**[[5z4m]] – DmTUTT (mutant) + UTP <br />
 +
 
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:06, 9 March 2022

RNA uridylyltransferase-4 complex with UTP, UMP and Mg+2 ions (green) (PDB entry 2q0f)

Drag the structure with the mouse to rotate

3D Structures of RNA uridylyltransferase

Updated on 09-March-2022

References

  1. Stagno J, Aphasizheva I, Rosengarth A, Luecke H, Aphasizhev R. UTP-bound and Apo structures of a minimal RNA uridylyltransferase. J Mol Biol. 2007 Feb 23;366(3):882-99. Epub 2006 Dec 2. PMID:17189640 doi:10.1016/j.jmb.2006.11.065
  2. Bortolamiol-Becet D, Hu F, Jee D, Wen J, Okamura K, Lin CJ, Ameres SL, Lai EC. Selective Suppression of the Splicing-Mediated MicroRNA Pathway by the Terminal Uridyltransferase Tailor. Mol Cell. 2015 Jul 16;59(2):217-28. doi: 10.1016/j.molcel.2015.05.034. Epub 2015 , Jul 2. PMID:26145174 doi:http://dx.doi.org/10.1016/j.molcel.2015.05.034
  3. Stagno J, Aphasizheva I, Aphasizhev R, Luecke H. Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14634-9. Epub 2007 Sep 4. PMID:17785418

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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