3gix
From Proteopedia
(Difference between revisions)
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==Crystal structure of human splicing factor dim2== | ==Crystal structure of human splicing factor dim2== | ||
| - | <StructureSection load='3gix' size='340' side='right' caption='[[3gix]], [[Resolution|resolution]] 1.33Å' scene=''> | + | <StructureSection load='3gix' size='340' side='right'caption='[[3gix]], [[Resolution|resolution]] 1.33Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3gix]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3gix]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GIX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GIX FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand= | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xbs|1xbs]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xbs|1xbs]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DIM2, DLP, TXNL4B ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DIM2, DLP, TXNL4B ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gix FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gix OCA], [https://pdbe.org/3gix PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gix RCSB], [https://www.ebi.ac.uk/pdbsum/3gix PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gix ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/TXN4B_HUMAN TXN4B_HUMAN]] Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition.<ref>PMID:15161931</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Guo, F]] | [[Category: Guo, F]] | ||
[[Category: Jin, T C]] | [[Category: Jin, T C]] | ||
Revision as of 08:06, 9 March 2022
Crystal structure of human splicing factor dim2
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Categories: Human | Large Structures | Guo, F | Jin, T C | Zhang, Y Z | Cell cycle | Dlp | Mrna processing | Mrna splicing | Nucleus | Phosphoprotein | Pre-mrna splicing | Splicing | Txnl4b
