Serine palmitoyltransferase
From Proteopedia
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==3D structures of serine palmitoyltransferase== | ==3D structures of serine palmitoyltransferase== | ||
| - | + | [[Serine palmitoyltransferase 3D structures]] | |
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| + | [[7k0l]] – hSPT1 + SPT2 + SPT small subunit A + antibiotic + PLP – human – Cryo EM<br /> | ||
| + | [[7k0k]] – hSPT1 + SPT2 + SPT small subunit A + sphinganine derivative – Cryo EM<br /> | ||
| + | [[7k0i]], [[7k0j]] – hSPT1 + SPT2 + SPT small subunit A – Cryo EM<br /> | ||
| + | [[7k0q]] – hSPT1 + SPT2 + SPT small subunit A + ORM1-like protein + antibiotic + PLP – Cryo EM<br /> | ||
| + | [[6m4n]], [[6m4o]], [[7k0m]], [[7k0n]], [[7k0o]], [7k0p]] – hSPT1 + SPT2 + SPT small subunit A + ORM1-like protein + PLP – Cryo EM<br /> | ||
| + | [[7cqi]], [[7cqk]] – hSPT1 + SPT2 + SPT small subunit A + ORM1-like protein + PLP derivative + substrate – Cryo EM<br /> | ||
[[2jg2]] – PpSPT + aldimine – ''Pseudomonas paucimobilis''<br /> | [[2jg2]] – PpSPT + aldimine – ''Pseudomonas paucimobilis''<br /> | ||
[[2jgt]] – PpSPT<br /> | [[2jgt]] – PpSPT<br /> | ||
[[2w8j]] - SpSPT + aldimine – ''Sphingomonas paucimobilis''<br /> | [[2w8j]] - SpSPT + aldimine – ''Sphingomonas paucimobilis''<br /> | ||
[[2w8t]], [[2w8u]], [[2w8v]], [[2w8w]] - SpSPT (mutant) + aldimine<br /> | [[2w8t]], [[2w8u]], [[2w8v]], [[2w8w]] - SpSPT (mutant) + aldimine<br /> | ||
| - | [[4bmk]] - SpSPT (mutant) + | + | [[4bmk]] - SpSPT (mutant) + antibiotic + PLP<br /> |
[[2xbn]] – SpSPT + pyridoxamine phosphate<br /> | [[2xbn]] – SpSPT + pyridoxamine phosphate<br /> | ||
[[3a2b]] – SPT + pyridoxal phosphate + serine – ''Sphingobacterium multivorum''<br /> | [[3a2b]] – SPT + pyridoxal phosphate + serine – ''Sphingobacterium multivorum''<br /> | ||
[[2x8u]] - SwSPT + pyridoxal derivative – ''Sphingomonas wittichii''<br /> | [[2x8u]] - SwSPT + pyridoxal derivative – ''Sphingomonas wittichii''<br /> | ||
| + | [[7e13]] - SPT + PLP – ''Erigeron canadensis''<br /> | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 11:16, 15 March 2022
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3D structures of serine palmitoyltransferase
Serine palmitoyltransferase 3D structures Updated on 15-March-2022
7k0l – hSPT1 + SPT2 + SPT small subunit A + antibiotic + PLP – human – Cryo EM
7k0k – hSPT1 + SPT2 + SPT small subunit A + sphinganine derivative – Cryo EM
7k0i, 7k0j – hSPT1 + SPT2 + SPT small subunit A – Cryo EM
7k0q – hSPT1 + SPT2 + SPT small subunit A + ORM1-like protein + antibiotic + PLP – Cryo EM
6m4n, 6m4o, 7k0m, 7k0n, 7k0o, [7k0p]] – hSPT1 + SPT2 + SPT small subunit A + ORM1-like protein + PLP – Cryo EM
7cqi, 7cqk – hSPT1 + SPT2 + SPT small subunit A + ORM1-like protein + PLP derivative + substrate – Cryo EM
2jg2 – PpSPT + aldimine – Pseudomonas paucimobilis
2jgt – PpSPT
2w8j - SpSPT + aldimine – Sphingomonas paucimobilis
2w8t, 2w8u, 2w8v, 2w8w - SpSPT (mutant) + aldimine
4bmk - SpSPT (mutant) + antibiotic + PLP
2xbn – SpSPT + pyridoxamine phosphate
3a2b – SPT + pyridoxal phosphate + serine – Sphingobacterium multivorum
2x8u - SwSPT + pyridoxal derivative – Sphingomonas wittichii
7e13 - SPT + PLP – Erigeron canadensis
References
- ↑ Hanada K. Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism. Biochim Biophys Acta. 2003 Jun 10;1632(1-3):16-30. PMID:12782147
- ↑ Ikushiro H, Islam MM, Okamoto A, Hoseki J, Murakawa T, Fujii S, Miyahara I, Hayashi H. Structural insights into the enzymatic mechanism of serine palmitoyltransferase from Sphingobacterium multivorum. J Biochem. 2009 Oct;146(4):549-62. Epub 2009 Jun 29. PMID:19564159 doi:10.1093/jb/mvp100
