1gnd

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1gnd.gif|left|200px]]
[[Image:1gnd.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1gnd |SIZE=350|CAPTION= <scene name='initialview01'>1gnd</scene>, resolution 1.81&Aring;
+
The line below this paragraph, containing "STRUCTURE_1gnd", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND=
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE= BOVGDI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1gnd| PDB=1gnd | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gnd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gnd OCA], [http://www.ebi.ac.uk/pdbsum/1gnd PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1gnd RCSB]</span>
+
-
}}
+
'''GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM'''
'''GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM'''
Line 34: Line 31:
[[Category: Wu, S K.]]
[[Category: Wu, S K.]]
[[Category: Zeng, K.]]
[[Category: Zeng, K.]]
-
[[Category: gtpase activation]]
+
[[Category: Gtpase activation]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 17:46:46 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 20:47:30 2008''
+

Revision as of 14:46, 2 May 2008

Image:1gnd.gif

Template:STRUCTURE 1gnd

GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM


Overview

The crystal structure of the bovine alpha-isoform of Rab GDP-dissociation inhibitor (GDI), which functions in vesicle-membrane transport to recycle and regulate Rab GTPases, has been determined to a resolution of 1.81 A. GDI is constructed of two main structural units, a large complex multisheet domain I and a smaller alpha-helical domain II. The structural organization of domain I is surprisingly closely related to FAD-containing monooxygenases and oxidases. Sequence-conserved regions common to GDI and the choroideraemia gene product, which delivers Rab to catalytic subunits of Rab geranylgeranyltransferase II, are clustered on one face of the molecule. The two most sequence-conserved regions, which form a compact structure at the apex of GDI, are shown by site-directed mutagenesis to play a critical role in the binding of Rab proteins.

About this Structure

1GND is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Structure and mutational analysis of Rab GDP-dissociation inhibitor., Schalk I, Zeng K, Wu SK, Stura EA, Matteson J, Huang M, Tandon A, Wilson IA, Balch WE, Nature. 1996 May 2;381(6577):42-8. PMID:8609986 Page seeded by OCA on Fri May 2 17:46:46 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1gnd"
Personal tools