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3gwv
From Proteopedia
(Difference between revisions)
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==Leucine transporter LeuT in complex with R-fluoxetine== | ==Leucine transporter LeuT in complex with R-fluoxetine== | ||
| - | <StructureSection load='3gwv' size='340' side='right' caption='[[3gwv]], [[Resolution|resolution]] 2.35Å' scene=''> | + | <StructureSection load='3gwv' size='340' side='right'caption='[[3gwv]], [[Resolution|resolution]] 2.35Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3gwv]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3gwv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquae Aquae]. The August 2013 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Serotonin Receptor'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2013_8 10.2210/rcsb_pdb/mom_2013_8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GWV FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RFX:(3R)-N-METHYL-3-PHENYL-3-[4-(TRIFLUOROMETHYL)PHENOXY]PROPAN-1-AMINE'>RFX</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LEU:LEUCINE'>LEU</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RFX:(3R)-N-METHYL-3-PHENYL-3-[4-(TRIFLUOROMETHYL)PHENOXY]PROPAN-1-AMINE'>RFX</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3gwu|3gwu]], [[3gww|3gww]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3gwu|3gwu]], [[3gww|3gww]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aq_2077, LeuT, snf ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aq_2077, LeuT, snf ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gwv OCA], [https://pdbe.org/3gwv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gwv RCSB], [https://www.ebi.ac.uk/pdbsum/3gwv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gwv ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gw/3gwv_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gw/3gwv_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</div> | </div> | ||
<div class="pdbe-citations 3gwv" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 3gwv" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Leucine transporter|Leucine transporter]] | ||
| + | *[[Serotonin Transporter|Serotonin Transporter]] | ||
| + | *[[Symporter 3D structures|Symporter 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Aquae]] | [[Category: Aquae]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Serotonin Receptor]] | [[Category: Serotonin Receptor]] | ||
Revision as of 07:57, 16 March 2022
Leucine transporter LeuT in complex with R-fluoxetine
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Categories: Aquae | Large Structures | RCSB PDB Molecule of the Month | Serotonin Receptor | Karpowich, N K | Law, C J | Reith, M E.A | Wang, D N | Zhen, J | Zhou, Z | Antidepressant | Integral membrane protein | Neurotransmitter | Nss | Symport | Transmembrane | Transmembrane transport | Transport | Transport protein
