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3h2u

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==Human raver1 RRM1, RRM2, and RRM3 domains in complex with human vinculin tail domain Vt==
==Human raver1 RRM1, RRM2, and RRM3 domains in complex with human vinculin tail domain Vt==
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<StructureSection load='3h2u' size='340' side='right' caption='[[3h2u]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
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<StructureSection load='3h2u' size='340' side='right'caption='[[3h2u]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3h2u]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H2U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3H2U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3h2u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H2U FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rke|1rke]], [[1tr2|1tr2]], [[3h2v|3h2v]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1rke|1rke]], [[1tr2|1tr2]], [[3h2v|3h2v]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RAVER1, KIAA1978 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RAVER1, KIAA1978 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3h2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h2u OCA], [http://pdbe.org/3h2u PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3h2u RCSB], [http://www.ebi.ac.uk/pdbsum/3h2u PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3h2u ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h2u OCA], [https://pdbe.org/3h2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h2u RCSB], [https://www.ebi.ac.uk/pdbsum/3h2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h2u ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RAVR1_HUMAN RAVR1_HUMAN]] Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).
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[[https://www.uniprot.org/uniprot/RAVR1_HUMAN RAVR1_HUMAN]] Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Izard, T]]
[[Category: Izard, T]]
[[Category: Lee, J H]]
[[Category: Lee, J H]]

Revision as of 08:01, 16 March 2022

Human raver1 RRM1, RRM2, and RRM3 domains in complex with human vinculin tail domain Vt

PDB ID 3h2u

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