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3hh7

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Current revision (12:47, 23 March 2022) (edit) (undo)
 
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<StructureSection load='3hh7' size='340' side='right'caption='[[3hh7]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
<StructureSection load='3hh7' size='340' side='right'caption='[[3hh7]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hh7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ophiophagus_hannah Ophiophagus hannah]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HH7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HH7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hh7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ophiophagus_hannah Ophiophagus hannah]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HH7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HH7 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hh7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hh7 OCA], [http://pdbe.org/3hh7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hh7 RCSB], [http://www.ebi.ac.uk/pdbsum/3hh7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hh7 ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hh7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hh7 OCA], [https://pdbe.org/3hh7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hh7 RCSB], [https://www.ebi.ac.uk/pdbsum/3hh7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hh7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TML3H_OPHHA TML3H_OPHHA]] Antagonist of muscle and neuronal nicotinic acetylcholine receptors (nAChR) with highest affinity for alpha(7)-nAChRs.<ref>PMID:20071329</ref>
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[[https://www.uniprot.org/uniprot/TML3H_OPHHA TML3H_OPHHA]] Antagonist of muscle and neuronal nicotinic acetylcholine receptors (nAChR) with highest affinity for alpha(7)-nAChRs.<ref>PMID:20071329</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Current revision

Structural and Functional Characterization of a Novel Homodimeric Three-finger Neurotoxin from the Venom of Ophiophagus hannah (King Cobra)

PDB ID 3hh7

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