3hiw

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<StructureSection load='3hiw' size='340' side='right'caption='[[3hiw]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3hiw' size='340' side='right'caption='[[3hiw]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hiw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Common_soapwort Common soapwort]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HIW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HIW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hiw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Common_soapwort Common soapwort]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HIW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HIW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=C2X:9,9-{(2R,3R,3AR,5S,7AR,9R,10R,10AR,12S,23R,25AR,27R,28R,28AR,30S,32AR,35AR,37S,39AR)-9-(6-AMINO-9H-PURIN-9-YL)-34-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-5,12,23,30,37-PENTAHYDROXY-3,10,28-TRIMETHOXY-5,12,23,30,37-PENTAOXIDOTETRACOSAHYDRO-2H,7H,25H-TRIFURO[3,2-F 3,2-L 3,2-X]PYRROLO[3,4-R][1,3,5,9,11,15,17,21,23,27,29,2,4,10,16,22,28]UNDECAOXAZAPENTAPHOSPHACYCLOPENTATRIACONTINE-2,27-DIYL}BIS(2-AMINO-3,9-DIHYDRO-6H-PURIN-6-ONE)'>C2X</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C2X:9,9-{(2R,3R,3AR,5S,7AR,9R,10R,10AR,12S,23R,25AR,27R,28R,28AR,30S,32AR,35AR,37S,39AR)-9-(6-AMINO-9H-PURIN-9-YL)-34-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-5,12,23,30,37-PENTAHYDROXY-3,10,28-TRIMETHOXY-5,12,23,30,37-PENTAOXIDOTETRACOSAHYDRO-2H,7H,25H-TRIFURO[3,2-F 3,2-L 3,2-X]PYRROLO[3,4-R][1,3,5,9,11,15,17,21,23,27,29,2,4,10,16,22,28]UNDECAOXAZAPENTAPHOSPHACYCLOPENTATRIACONTINE-2,27-DIYL}BIS(2-AMINO-3,9-DIHYDRO-6H-PURIN-6-ONE)'>C2X</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hio|3hio]], [[3hiq|3hiq]], [[3his|3his]], [[3hit|3hit]], [[3hiv|3hiv]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3hio|3hio]], [[3hiq|3hiq]], [[3his|3his]], [[3hit|3hit]], [[3hiv|3hiv]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hiw OCA], [http://pdbe.org/3hiw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hiw RCSB], [http://www.ebi.ac.uk/pdbsum/3hiw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hiw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hiw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hiw OCA], [https://pdbe.org/3hiw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hiw RCSB], [https://www.ebi.ac.uk/pdbsum/3hiw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hiw ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==

Revision as of 12:49, 23 March 2022

Crystal structure of Saporin-L1 in complex with the cyclic tetranucleotide inhibitor, a transition state analogue

PDB ID 3hiw

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