2vv5
From Proteopedia
(Difference between revisions)
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<StructureSection load='2vv5' size='340' side='right'caption='[[2vv5]], [[Resolution|resolution]] 3.45Å' scene=''> | <StructureSection load='2vv5' size='340' side='right'caption='[[2vv5]], [[Resolution|resolution]] 3.45Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2vv5]] is a 7 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2vv5]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. The November 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Mechanosensitive Channels'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_11 10.2210/rcsb_pdb/mom_2008_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VV5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VV5 FirstGlance]. <br> |
- | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vv5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vv5 OCA], [https://pdbe.org/2vv5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vv5 RCSB], [https://www.ebi.ac.uk/pdbsum/2vv5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vv5 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/MSCS_ECO57 MSCS_ECO57]] Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions. The channel is sensitive to voltage (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Ion channels 3D structures|Ion channels 3D structures]] | *[[Ion channels 3D structures|Ion channels 3D structures]] | ||
- | *[[Mechanosensitive channels: opening and closing|Mechanosensitive channels: opening and closing]] | ||
== References == | == References == | ||
<references/> | <references/> |
Revision as of 11:46, 30 March 2022
The open structure of MscS
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Categories: Bacillus coli migula 1895 | Large Structures | Mechanosensitive Channels | RCSB PDB Molecule of the Month | Dong, C | Johnson, K A | Naismith, J H | Wang, W | Inner membrane | Ion transport | Ionic channel | Membrane | Membrane protein | Membrane structure | Open channel | Transmembrane | Transport