2w08

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<StructureSection load='2w08' size='340' side='right'caption='[[2w08]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='2w08' size='340' side='right'caption='[[2w08]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2w08]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W08 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2W08 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2w08]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W08 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2a3x|2a3x]], [[1sac|1sac]], [[1gyk|1gyk]], [[2a3y|2a3y]], [[2a3w|2a3w]], [[1lgn|1lgn]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2a3x|2a3x]], [[1sac|1sac]], [[1gyk|1gyk]], [[2a3y|2a3y]], [[2a3w|2a3w]], [[1lgn|1lgn]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2w08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w08 OCA], [http://pdbe.org/2w08 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w08 RCSB], [http://www.ebi.ac.uk/pdbsum/2w08 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w08 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w08 OCA], [https://pdbe.org/2w08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w08 RCSB], [https://www.ebi.ac.uk/pdbsum/2w08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w08 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[http://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
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[[https://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
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[[https://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 2w08" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2w08" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Serum amyloid P-component|Serum amyloid P-component]]
== References ==
== References ==
<references/>
<references/>

Revision as of 11:49, 30 March 2022

The structure of serum amyloid P component bound to 0-phospho- threonine

PDB ID 2w08

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