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2w10

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<StructureSection load='2w10' size='340' side='right'caption='[[2w10]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='2w10' size='340' side='right'caption='[[2w10]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2w10]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W10 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2W10 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2w10]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W10 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W10 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2d0n|2d0n]], [[1r1q|1r1q]], [[1h3h|1h3h]], [[1r1s|1r1s]], [[1oeb|1oeb]], [[1uti|1uti]], [[1r1p|1r1p]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2d0n|2d0n]], [[1r1q|1r1q]], [[1h3h|1h3h]], [[1r1s|1r1s]], [[1oeb|1oeb]], [[1uti|1uti]], [[1r1p|1r1p]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2w10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w10 OCA], [http://pdbe.org/2w10 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w10 RCSB], [http://www.ebi.ac.uk/pdbsum/2w10 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w10 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w10 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w10 OCA], [https://pdbe.org/2w10 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w10 RCSB], [https://www.ebi.ac.uk/pdbsum/2w10 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w10 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PTN23_MOUSE PTN23_MOUSE]] May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
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[[https://www.uniprot.org/uniprot/PTN23_MOUSE PTN23_MOUSE]] May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 11:50, 30 March 2022

Mona SH3C in complex

PDB ID 2w10

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