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2w1b

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<StructureSection load='2w1b' size='340' side='right'caption='[[2w1b]], [[Resolution|resolution]] 3.85&Aring;' scene=''>
<StructureSection load='2w1b' size='340' side='right'caption='[[2w1b]], [[Resolution|resolution]] 3.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2w1b]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W1B OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2W1B FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2w1b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W1B FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DXC:(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC+ACID'>DXC</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DXC:(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC+ACID'>DXC</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1oy8|1oy8]], [[1t9u|1t9u]], [[1iwg|1iwg]], [[1t9t|1t9t]], [[1t9y|1t9y]], [[1t9w|1t9w]], [[2j8s|2j8s]], [[1oy6|1oy6]], [[1t9x|1t9x]], [[2gif|2gif]], [[2hrt|2hrt]], [[1oye|1oye]], [[1oyd|1oyd]], [[1oy9|1oy9]], [[1t9v|1t9v]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1oy8|1oy8]], [[1t9u|1t9u]], [[1iwg|1iwg]], [[1t9t|1t9t]], [[1t9y|1t9y]], [[1t9w|1t9w]], [[2j8s|2j8s]], [[1oy6|1oy6]], [[1t9x|1t9x]], [[2gif|2gif]], [[2hrt|2hrt]], [[1oye|1oye]], [[1oyd|1oyd]], [[1oy9|1oy9]], [[1t9v|1t9v]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2w1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w1b OCA], [http://pdbe.org/2w1b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w1b RCSB], [http://www.ebi.ac.uk/pdbsum/2w1b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w1b ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w1b OCA], [https://pdbe.org/2w1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w1b RCSB], [https://www.ebi.ac.uk/pdbsum/2w1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w1b ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI]] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
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[[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI]] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 11:50, 30 March 2022

The structure of the efflux pump AcrB in complex with bile acid

PDB ID 2w1b

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