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3hqg

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==Crystal structure of restriction endonuclease EcoRII catalytic C-terminal domain in complex with cognate DNA==
==Crystal structure of restriction endonuclease EcoRII catalytic C-terminal domain in complex with cognate DNA==
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<StructureSection load='3hqg' size='340' side='right' caption='[[3hqg]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='3hqg' size='340' side='right'caption='[[3hqg]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3hqg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HQG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3HQG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3hqg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HQG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1na6|1na6]], [[3hqf|3hqf]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1na6|1na6]], [[3hqf|3hqf]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ECORII, ecoRIIR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ECORII, ecoRIIR ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3hqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hqg OCA], [http://pdbe.org/3hqg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3hqg RCSB], [http://www.ebi.ac.uk/pdbsum/3hqg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3hqg ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hqg OCA], [https://pdbe.org/3hqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hqg RCSB], [https://www.ebi.ac.uk/pdbsum/3hqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hqg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/T2E2_ECOLX T2E2_ECOLX]] Recognizes the double-stranded sequence CCWGG and cleaves before C-1.
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[[https://www.uniprot.org/uniprot/T2E2_ECOLX T2E2_ECOLX]] Recognizes the double-stranded sequence CCWGG and cleaves before C-1.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Endonuclease|Endonuclease]]
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*[[Endonuclease 3D structures|Endonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Bacillus coli migula 1895]]
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[[Category: Large Structures]]
[[Category: Type II site-specific deoxyribonuclease]]
[[Category: Type II site-specific deoxyribonuclease]]
[[Category: Golovenko, D]]
[[Category: Golovenko, D]]

Revision as of 11:54, 30 March 2022

Crystal structure of restriction endonuclease EcoRII catalytic C-terminal domain in complex with cognate DNA

PDB ID 3hqg

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