3htz
From Proteopedia
(Difference between revisions)
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==Crystal Structure of the catalytic fragment of alanyl-tRNA synthetase in complex with L-serine: Re-refined== | ==Crystal Structure of the catalytic fragment of alanyl-tRNA synthetase in complex with L-serine: Re-refined== | ||
| - | <StructureSection load='3htz' size='340' side='right' caption='[[3htz]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='3htz' size='340' side='right'caption='[[3htz]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3htz]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3htz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HTZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HTZ FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ygb|1ygb]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ygb|1ygb]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">alaS, aq_1293 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">alaS, aq_1293 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 "Aquifex aeolicus" Huber and Stetter 2001])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Alanine--tRNA_ligase Alanine--tRNA ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.7 6.1.1.7] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3htz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3htz OCA], [https://pdbe.org/3htz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3htz RCSB], [https://www.ebi.ac.uk/pdbsum/3htz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3htz ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/SYA_AQUAE SYA_AQUAE]] Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity).[HAMAP-Rule:MF_00036] |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Aminoacyl tRNA | + | *[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Aquifex aeolicus huber and stetter 2001]] | [[Category: Aquifex aeolicus huber and stetter 2001]] | ||
[[Category: Alanine--tRNA ligase]] | [[Category: Alanine--tRNA ligase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Guo, M]] | [[Category: Guo, M]] | ||
[[Category: Schimmel, P]] | [[Category: Schimmel, P]] | ||
Revision as of 11:57, 30 March 2022
Crystal Structure of the catalytic fragment of alanyl-tRNA synthetase in complex with L-serine: Re-refined
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Categories: Aquifex aeolicus huber and stetter 2001 | Alanine--tRNA ligase | Large Structures | Guo, M | Schimmel, P | Swairjo, M A | Adenosine triphosphate | Alanine-trna ligase | Aminoacyl-trna synthetase | Atp-binding | Binding site | Cytoplasm | Genetic code | Ligase | Nucleotide-binding | Protein biosynthesis | Protein conformation
