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Signal recognition particle protein
From Proteopedia
(Difference between revisions)
| Line 9: | Line 9: | ||
*Signal recognition particle | *Signal recognition particle | ||
| - | **[[6y2z | + | **[[6y2z]] – hSRP54 NG domain 1-296 - human<br /> |
| - | **[[6y30]] – hSRP54 NG domain (mutant)<br /> | + | **[[6y30]], [[6y31]] – hSRP54 NG domain (mutant)<br /> |
**[[1qb2]] – hSRP54 M domain 326-434<br /> | **[[1qb2]] – hSRP54 M domain 326-434<br /> | ||
**[[4p3f]] – hSRP68 (mutant)<br /> | **[[4p3f]] – hSRP68 (mutant)<br /> | ||
| Line 44: | Line 44: | ||
**[[2j37]] - hSRP19 + SRP54 + ribosomal proteins L23, L31, L35 + RNA – Cryo EM<BR /> | **[[2j37]] - hSRP19 + SRP54 + ribosomal proteins L23, L31, L35 + RNA – Cryo EM<BR /> | ||
**[[2go5]] – dSRP19 + SRP54 + hSRP receptor α subunit + mSRP receptor b subunit + ribosomal proteins L23, L31, L35 + RNA – dog<br /> | **[[2go5]] – dSRP19 + SRP54 + hSRP receptor α subunit + mSRP receptor b subunit + ribosomal proteins L23, L31, L35 + RNA – dog<br /> | ||
| + | **[[7obq]], [[7obr]] – dSRP19 + SRP54 + SRP68 + SRP72 + SRP receptor ubunit a + RNA – Cryo EM<br /> | ||
**[[4ue5]] – dSRP9 + SRP14 + SRP54 + SRP68 + RNA – Cryo EM<br /> | **[[4ue5]] – dSRP9 + SRP14 + SRP54 + SRP68 + RNA – Cryo EM<br /> | ||
**[[3ktw]] - SsSRP19 + RNA S domain <br /> | **[[3ktw]] - SsSRP19 + RNA S domain <br /> | ||
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**[[2xkv]] - EcSRP54-like NG+M domains + 4.5SRNA – Cryo EM<BR /> | **[[2xkv]] - EcSRP54-like NG+M domains + 4.5SRNA – Cryo EM<BR /> | ||
**[[2xxa]] - EcSRP54-like residues 1-433 (mutant) + cell division protein FtsY residues 196-497+ 4.5SRNA<br /> | **[[2xxa]] - EcSRP54-like residues 1-433 (mutant) + cell division protein FtsY residues 196-497+ 4.5SRNA<br /> | ||
| + | **[[7o9f]], [[7o9g]], [[7o9i]] - EcSRP54-like residues 2-299 + ppGpp<br /> | ||
**[[3zn8]] - EcSRP54 NG domain + cell division protein FtsY residues 201-495+ 4.5SRNA + dipeptidyl aminopeptidase B<br /> | **[[3zn8]] - EcSRP54 NG domain + cell division protein FtsY residues 201-495+ 4.5SRNA + dipeptidyl aminopeptidase B<br /> | ||
**[[2pxb]], [[2pxd]], [[2pxe]], [[2pxf]], [[2pxk]], [[2pxl]], [[2pxq]], [[2pxq]], [[2pxt]], [[2pxu]], [[2pxv]] - EcSRP54-like C terminal + 4.5SRNA domain IV (mutant)<br /> | **[[2pxb]], [[2pxd]], [[2pxe]], [[2pxf]], [[2pxk]], [[2pxl]], [[2pxq]], [[2pxq]], [[2pxt]], [[2pxu]], [[2pxv]] - EcSRP54-like C terminal + 4.5SRNA domain IV (mutant)<br /> | ||
**[[2j28]] – EcSRP54-like + 70S ribosome – Cryo EM<BR /> | **[[2j28]] – EcSRP54-like + 70S ribosome – Cryo EM<BR /> | ||
| - | **[[4ue4]] – | + | **[[4ue4]] – BsSRP M domain + FtsQ signal sequence + RNA - ''Bacillus subtilis''<br /> |
| + | **[[7o5b]] – BsSRP in 70S ribosome + ppGpp – Cryo EM<BR /> | ||
*Other signal recognition particle complexes | *Other signal recognition particle complexes | ||
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**[[3kl4]] – SsSRP54 residues 2-432 + polypeptide<br /> | **[[3kl4]] – SsSRP54 residues 2-432 + polypeptide<br /> | ||
**[[5l3v]] - SsSRP54 + GDP<br /> | **[[5l3v]] - SsSRP54 + GDP<br /> | ||
| + | **[[7epk]] - SRP54 + GDP – ''Aeropyrum pernix''<br /> | ||
**[[4c7o]] – EcSRP + FtsY + SRP RNA<br /> | **[[4c7o]] – EcSRP + FtsY + SRP RNA<br /> | ||
Revision as of 08:52, 6 April 2022
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3D structures of signal recognition particle
Updated on 06-April-2022
References
- ↑ Halic M, Beckmann R. The signal recognition particle and its interactions during protein targeting. Curr Opin Struct Biol. 2005 Feb;15(1):116-25. PMID:15718142 doi:http://dx.doi.org/10.1016/j.sbi.2005.01.013
- ↑ Bovia F, Fornallaz M, Leffers H, Strub K. The SRP9/14 subunit of the signal recognition particle (SRP) is present in more than 20-fold excess over SRP in primate cells and exists primarily free but also in complex with small cytoplasmic Alu RNAs. Mol Biol Cell. 1995 Apr;6(4):471-84. PMID:7542942
- ↑ Dean KA, von Ahsen O, Gorlich D, Fried HM. Signal recognition particle protein 19 is imported into the nucleus by importin 8 (RanBP8) and transportin. J Cell Sci. 2001 Oct;114(Pt 19):3479-85. PMID:11682607
- ↑ Gowda K, Black SD, Moeller I, Sakakibara Y, Liu MC, Zwieb C. Protein SRP54 of human signal recognition particle: cloning, expression, and comparative analysis of functional sites. Gene. 1998 Jan 30;207(2):197-207. PMID:9511762
- ↑ Lutcke H, Prehn S, Ashford AJ, Remus M, Frank R, Dobberstein B. Assembly of the 68- and 72-kD proteins of signal recognition particle with 7S RNA. J Cell Biol. 1993 Jun;121(5):977-85. PMID:8388879
