This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7e17
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Structure of dimeric uPAR== | ==Structure of dimeric uPAR== | ||
| - | <StructureSection load='7e17' size='340' side='right'caption='[[7e17]]' scene=''> | + | <StructureSection load='7e17' size='340' side='right'caption='[[7e17]], [[Resolution|resolution]] 2.96Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7E17 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7E17 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7e17]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7E17 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7E17 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7e17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7e17 OCA], [https://pdbe.org/7e17 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7e17 RCSB], [https://www.ebi.ac.uk/pdbsum/7e17 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7e17 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7e17 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7e17 OCA], [https://pdbe.org/7e17 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7e17 RCSB], [https://www.ebi.ac.uk/pdbsum/7e17 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7e17 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/UPAR_HUMAN UPAR_HUMAN]] Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Cai Y]] | + | [[Category: Cai, Y]] |
| - | [[Category: Huang M]] | + | [[Category: Huang, M]] |
| + | [[Category: Cell invasion]] | ||
| + | [[Category: Gpi-anchored protein]] | ||
Revision as of 10:30, 6 April 2022
Structure of dimeric uPAR
| |||||||||||
