2wh5
From Proteopedia
(Difference between revisions)
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<StructureSection load='2wh5' size='340' side='right'caption='[[2wh5]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='2wh5' size='340' side='right'caption='[[2wh5]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2wh5]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2wh5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WH5 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=ST9:STEAROYL-COENZYME+A'>ST9</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=ST9:STEAROYL-COENZYME+A'>ST9</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh5 OCA], [https://pdbe.org/2wh5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wh5 RCSB], [https://www.ebi.ac.uk/pdbsum/2wh5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wh5 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/ACBD4_HUMAN ACBD4_HUMAN]] Binds medium- and long-chain acyl-CoA esters and may function as an intracellular carrier of acyl-CoA esters. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] |
Revision as of 11:07, 6 April 2022
Crystal structure of human acyl-CoA binding domain 4 complexed with stearoyl-CoA
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Categories: Human | Large Structures | Arrowsmith, C | Bountra, C | Chaikuad, A | Delft, F von | Edwards, A | Johansson, C | Oppermann, U | Roos, A K | Salah, E | Savitsky, P | Shafqat, N | Ugochukwu, E | Weigelt, J | Yue, W W | Acyl-coa binding | Alternative splicing | Fatty acid metabolism | Lipid binding protein | Lipid transport