Son of sevenless
From Proteopedia
(Difference between revisions)
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**[[1awe]] - hSOS1 PH - NMR <br /> | **[[1awe]] - hSOS1 PH - NMR <br /> | ||
**[[2ii0]] - hSOS1 REM+catalytic domains<br /> | **[[2ii0]] - hSOS1 REM+catalytic domains<br /> | ||
| - | **[[5ovd]] - hSOS1 REM+catalytic domains (mutant)<br /> | ||
**[[1dbh]] - hSOS1 DH+PH domains<br /> | **[[1dbh]] - hSOS1 DH+PH domains<br /> | ||
**[[1xd4]], [[1xdv]] - hSOS1 DH+PH+REM+catalytic domains<br /> | **[[1xd4]], [[1xdv]] - hSOS1 DH+PH+REM+catalytic domains<br /> | ||
**[[1pms]] - mSOS1 PH (mutant) - mouse - NMR <br /> | **[[1pms]] - mSOS1 PH (mutant) - mouse - NMR <br /> | ||
| - | |||
*Son of sevenless 1 complex | *Son of sevenless 1 complex | ||
| - | |||
| - | **[[6epl]] - hSOS1 REM+catalytic domains + KRas<br /> | ||
**[[1bkd]] - hSOS1 REM+catalytic domains + HRas<br /> | **[[1bkd]] - hSOS1 REM+catalytic domains + HRas<br /> | ||
**[[1xd2]] - hSOS1 REM+catalytic domains + HRas + GDP<br /> | **[[1xd2]] - hSOS1 REM+catalytic domains + HRas + GDP<br /> | ||
| + | |||
| + | *Son of sevenless 1 homolog | ||
| + | |||
| + | **[[5ovd]] - hSOS1 REM+catalytic domains (mutant)<br /> | ||
| + | **[[6scm]], [[6sfr]], [[7avi]], [[7avl]], [[7avs]], [[7avt]], [[7avu]], [[7avv]], [[7avs]] - hSOS1 REM+catalytic domains + inhibitor<br /> | ||
| + | **[[5ove]], [[5ovg]], [[5ovf]] [[5ovi]], [[5ovh]] - hSOS1 REM+catalytic domains (mutant) + inhibitor<br /> | ||
**[[1nvx]], [[1nvu]] - hSOS1 REM+catalytic domains + HRas + GTP<br /> | **[[1nvx]], [[1nvu]] - hSOS1 REM+catalytic domains + HRas + GTP<br /> | ||
**[[1nvw]], [[1nvv]] - hSOS1 REM+catalytic domains + HRas + GNP<br /> | **[[1nvw]], [[1nvv]] - hSOS1 REM+catalytic domains + HRas + GNP<br /> | ||
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**[[5wfo]], [[5wfq]], [[5fwp]], [[5fwr]] - hSOS1 REM+catalytic domains + HRas + GNP + ligand<br /> | **[[5wfo]], [[5wfq]], [[5fwp]], [[5fwr]] - hSOS1 REM+catalytic domains + HRas + GNP + ligand<br /> | ||
**[[6d5w]], [[6d5v]], [[6d5m]], [[6bvi]], [[6bvk]], [[6bvj]], [[6bvm]], [[6bvl]], [[6cuo]], [[6d5e]], [[6d59]], [[6d56]], [[6d55]], [[6d5h]], [[6d5g]], [[6d5j]], [[6d5l]], [[6cup]], [[6cur]], [[4nym]] - hSOS1 REM+catalytic domains + HRas + GNP + activator<br /> | **[[6d5w]], [[6d5v]], [[6d5m]], [[6bvi]], [[6bvk]], [[6bvj]], [[6bvm]], [[6bvl]], [[6cuo]], [[6d5e]], [[6d59]], [[6d56]], [[6d55]], [[6d5h]], [[6d5g]], [[6d5j]], [[6d5l]], [[6cup]], [[6cur]], [[4nym]] - hSOS1 REM+catalytic domains + HRas + GNP + activator<br /> | ||
| - | **[[6scm]], [[6sfr]] - hSOS1 REM+catalytic domains + inhibitor<br /> | ||
| - | **[[5ove]], [[5ovg]], [[5ovf]] [[5ovi]], [[5ovh]] - hSOS1 REM+catalytic domains (mutant) + inhibitor<br /> | ||
**[[4nyi]], [[4nyj]], [[6v94]], [[6v9j]], [[6v9l]], [[6v9n]], [[6v9m]], [[6v9f]] - hSOS1 REM+catalytic domains + HRas + GNP + inhibitor<br /> | **[[4nyi]], [[4nyj]], [[6v94]], [[6v9j]], [[6v9l]], [[6v9n]], [[6v9m]], [[6v9f]] - hSOS1 REM+catalytic domains + HRas + GNP + inhibitor<br /> | ||
| + | **[[6epl]] - hSOS1 REM+catalytic domains (mutant) + KRas<br /> | ||
| + | **[[7kfz]] - hSOS1 REM+catalytic domains + KRas + GNP – Cryo EM<br /> | ||
**[[6epn]], [[6epm]], [[6epp]], [[6epo]] - hSOS1 REM+catalytic domains + KRas + inhibitor<br /> | **[[6epn]], [[6epm]], [[6epp]], [[6epo]] - hSOS1 REM+catalytic domains + KRas + inhibitor<br /> | ||
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**[[6eie]] - hSOS2 REM+catalytic domains (mutant)<br /> | **[[6eie]] - hSOS2 REM+catalytic domains (mutant)<br /> | ||
| + | |||
}} | }} | ||
Revision as of 07:40, 7 April 2022
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3D structures of son of sevenless
Updated on 07-April-2022
References
- ↑ Rojas JM, Oliva JL, Santos E. Mammalian son of sevenless Guanine nucleotide exchange factors: old concepts and new perspectives. Genes Cancer. 2011 Mar;2(3):298-305. doi: 10.1177/1947601911408078. PMID:21779500 doi:http://dx.doi.org/10.1177/1947601911408078
- ↑ Pierre S, Bats AS, Coumoul X. Understanding SOS (Son of Sevenless). Biochem Pharmacol. 2011 Nov 1;82(9):1049-56. doi: 10.1016/j.bcp.2011.07.072. Epub, 2011 Jul 20. PMID:21787760 doi:http://dx.doi.org/10.1016/j.bcp.2011.07.072
