Nodal signaling pathway
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
<StructureSection load='4n1d' size='340' side='right' caption='Nodal/BMP2 chimera NB250' scene='90/909304/Cv/1'> | <StructureSection load='4n1d' size='340' side='right' caption='Nodal/BMP2 chimera NB250' scene='90/909304/Cv/1'> | ||
| - | The Nodal signaling pathway is a signal transduction pathway important in regional and cellular differentiation during embryonic development. The Nodal family of proteins, a subset of the [[transforming growth factor beta (TGFβ) superfamily]], is responsible for mesoendoderm induction, patterning of the nervous system, and determination of dorsal- ventral axis in vertebrate embryos. Activation of the Nodal pathway involves nodal binding to activin and activin-like receptors which leads to phosphorylation of the Smad2. | + | The Nodal signaling pathway is a signal transduction pathway important in regional and cellular differentiation during embryonic development. The Nodal family of proteins, a subset of the [[TGF beta signaling pathway#The TGF beta superfamily of ligands|transforming growth factor beta (TGFβ) superfamily]], is responsible for mesoendoderm induction, patterning of the nervous system, and determination of dorsal- ventral axis in vertebrate embryos. Activation of the Nodal pathway involves nodal binding to activin and activin-like receptors which leads to phosphorylation of the Smad2. |
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 13:16, 10 April 2022
| |||||||||||
