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2x6g

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<StructureSection load='2x6g' size='340' side='right'caption='[[2x6g]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
<StructureSection load='2x6g' size='340' side='right'caption='[[2x6g]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2x6g]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6G OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2X6G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2x6g]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X6G FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1b50|1b50]], [[1b53|1b53]], [[2x69|2x69]]</td></tr>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1b50|1b50]], [[1b53|1b53]], [[2x69|2x69]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2x6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6g OCA], [http://pdbe.org/2x6g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x6g RCSB], [http://www.ebi.ac.uk/pdbsum/2x6g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6g ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6g OCA], [https://pdbe.org/2x6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x6g RCSB], [https://www.ebi.ac.uk/pdbsum/2x6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CCL3_HUMAN CCL3_HUMAN]] Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).<ref>PMID:8525373</ref>
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[[https://www.uniprot.org/uniprot/CCL3_HUMAN CCL3_HUMAN]] Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).<ref>PMID:8525373</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Revision as of 10:46, 13 April 2022

X-ray Structure of Macrophage Inflammatory Protein-1 alpha (D27A)

PDB ID 2x6g

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