3i3x
From Proteopedia
(Difference between revisions)
Line 1: | Line 1: | ||
==Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA== | ==Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA== | ||
- | <StructureSection load='3i3x' size='340' side='right' caption='[[3i3x]], [[Resolution|resolution]] 2.10Å' scene=''> | + | <StructureSection load='3i3x' size='340' side='right'caption='[[3i3x]], [[Resolution|resolution]] 2.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3i3x]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3i3x]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/"leptospira_icteroides"_noguchi_1919 "leptospira icteroides" noguchi 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I3X FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U22:URIDINE-5-DIPHOSPHATE-3-N-(R-3-HYDROXYLAUROYL)-N-ACETYL-D-GLUCOSAMINE'>U22</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=U22:URIDINE-5-DIPHOSPHATE-3-N-(R-3-HYDROXYLAUROYL)-N-ACETYL-D-GLUCOSAMINE'>U22</scene></td></tr> |
- | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3i3a|3i3a]], [[3hsq|3hsq]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3i3a|3i3a]], [[3hsq|3hsq]]</div></td></tr> |
- | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LA3949, LA_3949, lpxA ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LA3949, LA_3949, lpxA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=173 "Leptospira icteroides" Noguchi 1919])</td></tr> |
- | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine_O-acyltransferase Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.129 2.3.1.129] </span></td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i3x OCA], [https://pdbe.org/3i3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i3x RCSB], [https://www.ebi.ac.uk/pdbsum/3i3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i3x ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [[ | + | [[https://www.uniprot.org/uniprot/Q8EZA6_LEPIN Q8EZA6_LEPIN]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.[SAAS:SAAS00064151] |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Line 39: | Line 39: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Leptospira icteroides noguchi 1919]] | [[Category: Leptospira icteroides noguchi 1919]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Williams, A H]] | [[Category: Williams, A H]] | ||
[[Category: Acyltransferase]] | [[Category: Acyltransferase]] |
Revision as of 10:57, 13 April 2022
Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA
|