Telomerase 3D structures

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[Telomerase]]
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==Telomerase 3D structures==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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[[3kyl]], [[3du5]], [[3du6]] – TERT+DNA – ''Tribolium castaneum''<br />
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*Telomerase reverse transcriptase
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[[2r4g]] – TtTERT RNA binding domain – ''Tetrahymena thermophila''<br />
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[[2b2a]] – TtTERT (mutant)<br />
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**[[5c9h]] – hTERT + RNA - human<br />
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[[2fey]] - TtTERC RNA P2b hairpin – NMR<br />
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**[[4mnq]] – hTERT + MHC + b-2-microglobulin + T cell receptor<br />
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[[1q75]], [[2k96]] – hTERC RNA P2b hairpin (mutant) – human – NMR<br />
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**[[5ugw]] – hTERT thumb domain<br />
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[[2k95]], [[1na2]] - hTERC RNA P2b hairpin – NMR<br />
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**[[7bg9]], [[7bgb]] – hTERT H/ACA RNP lobe – Cryo EM<br />
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[[2qh2]] - hTERC RNA CR7– NMR<br />
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**[[7qxa]] – hTERT + TPP1 + DNA – Cryo EM<br />
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[[1ymo]] - hTERC RNAstem loop IV– NMR<br />
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**[[7qxb]], [[7qxs]] – hTERT + TPP1 + POT1 + DNA – Cryo EM<br />
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[[1z31]] - hTERC RNA Pj6 hairpin – NMR<br />
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**[[4lmo]] – TERT RNA binding domain - puffer<br />
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**[[4o26]] – TERT + telomerase TR – rice fish<br />
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**[[3du6]], [[3du5]] - rfbTERT catalytic subunit - red flour beetle<br />
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**[[5cqg]] - rfbTERT + inhibitor <br />
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**[[3kyl]], [[6e53]], [[6uso]], [[6usq]], [[6usp]] - rfbTERT + DNA<br />
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**[[7kqm]], [[7kqn]] - rfbTERT telomerase catalytic subunit + DNA + RNA<br />
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**[[6usr]] - rfbTERT + DNA + G2P<br />
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**[[2b2a]] - TtTERT telomerase catalytic subunit (mutant) - ''Tetrahymena thermophila''<br />
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**[[2r4g]] - TtTERT telomerase catalytic subunit<br />
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**[[7lma]], [[7lmb]] – TtTERT + telomerase-associated protein + RNA + DNA – Cryo EM<br />
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**[[6d6v]] – TtTERT + telomerase-associated protein + TEB2 + RNA + DNA – Cryo EM<br />
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**[[5c9h]] - TtTERT catalytic subunit + DNA<br />
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**[[5lgf]] - OgTERT N-terminal - ''Ogataea polymorpha'' - NMR<br />
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**[[5npt]] – OgTERT N-terminal <br />
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**[[6zd1]], [[6zd2]], [[6zd6]] - CaTERT – ''Candida albicans''<br />
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**[[6zdp]], [[6zdq]], [[6zdu]] - CaTERT + RNA <br />
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[[Category:Topic Page]]
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*Telomerase RNA
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**[[7v99]], [[7v9a]] - hTERC in telomerase holoenzyme – Cryo EM<br />
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**[[1q75]], [[2k96]] – hTERC P2b hairpin (mutant) – human – NMR<br />
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**[[2k95]], [[1na2]] - hTERC P2b hairpin – NMR<br />
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**[[2l3e]] - hTERC P2a P2b hairpin – NMR<br />
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**[[2qh2]] - hTERC CR7– NMR<br />
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**[[1ymo]] - hTERC stem loop IV – NMR<br />
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**[[1z31]] - hTERC Pj6 hairpin – NMR<br />
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**[[2kye]] - hTERC P6.1 hairpin – NMR<br />
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**[[2qh3]], [[2qh4]] - hTERC terminal hairpin loop – NMR<br />
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**[[5kqe]] - TERC P2b hairpin – ''Oryzias latipes'' - NMR<br />
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**[[2fey]] - TtTERC P2b hairpin – NMR<br />
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**[[5kmz]] - TtTERC pseudoknot – NMR<br />
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**[[2m21]] - TtTERC stem loop IV – NMR<br />
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**[[2m22]] - TtTERC helix II – NMR<br />
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**[[2mhi]] - TERC CR4/5 – medaka - NMR<br />
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**[[2m8k]] - TERC pseudoknot – ''Kluyveromyces lactis'' - NMR<br />
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}}
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[[Category:Topic Page]]
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[[Telomerase]] (TEL) adds DNA repeats to the tail end of telomeres. It carries its own RNA. The human TEL is composed of 2 [[Telomerase Reverse Transcriptase]] (TERT), 2 Telomerase RNA (TERC) and 2 dyskerin (DKC1) molecules. For additional details see [[ Catalytic Subunit of T. Castaneum TERT Polymerase]].
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Revision as of 07:33, 19 April 2022

Telomerase 3D structures

Updated on 19-April-2022

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky

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