Benjamin Prywitch/Sandbox 1

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Introduction

Titin, (TITN) also known as Connectin (PDB 3b43) is a human protein, unique for its large size. It is the largest known protein chain in the entire human body, comprising over 34,000 amino acids and holding a molecular weight of 3800 kD. Titin is found within muscle fibers and classified as a connectin protein. An adult human that weighs 80 kg may contain almost half a kilogram of Titin, (Labeit). making it extremely abundant as well.

Discovery

Structure

Function

Medical Importance

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