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2yd5
From Proteopedia
(Difference between revisions)
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<StructureSection load='2yd5' size='340' side='right'caption='[[2yd5]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='2yd5' size='340' side='right'caption='[[2yd5]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2yd5]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2yd5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YD5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YD5 FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lar|1lar]], [[2yd6|2yd6]], [[2yd7|2yd7]], [[2yd1|2yd1]], [[2yd8|2yd8]], [[2yd2|2yd2]], [[2yd4|2yd4]], [[2yd9|2yd9]], [[2yd3|2yd3]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1lar|1lar]], [[2yd6|2yd6]], [[2yd7|2yd7]], [[2yd1|2yd1]], [[2yd8|2yd8]], [[2yd2|2yd2]], [[2yd4|2yd4]], [[2yd9|2yd9]], [[2yd3|2yd3]]</div></td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yd5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yd5 OCA], [https://pdbe.org/2yd5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yd5 RCSB], [https://www.ebi.ac.uk/pdbsum/2yd5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yd5 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/PTPRF_HUMAN PTPRF_HUMAN]] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).<ref>PMID:10338209</ref> The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.<ref>PMID:10338209</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 12:27, 27 April 2022
Crystal structure of the N-terminal Ig1-2 module of Human Receptor Protein Tyrosine Phosphatase LAR
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