Transcriptional activator 3D structures

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	{{#tree:id=OrganizedByTopic|openlevels=0|		{{#tree:id=OrganizedByTopic|openlevels=0|
-	*Gcn4 transcriptional activator see [[Gcn4]]	+	*Gcn4 TA See [[Gcn4]]
-	*Gcn5 transcriptional activator	+	*Gcn5 TA
	**[[1e6i]] – yTA brododomain + histone H4 peptide - yeast<br />		**[[1e6i]] – yTA brododomain + histone H4 peptide - yeast<br />
	**[[1ygh]] – yTA histone acetyltransferase domain <br />		**[[1ygh]] – yTA histone acetyltransferase domain <br />
-	*C-Myb transcriptional activator; domains - DBD repeat 1 38-89; DBD repeat 2 90-141; DBD repeat 3 142-193; transcriptional activation (TAD) 291-315	+	*C-Myb TA; domains – DBD ; DBD repeat 1 38-89; repeat 2 90-141; repeat 3 142-193; transcription activation 291-315
-	**[[1mse]], [[1msf]] – mTA DBD repeat 1,2 + DNA - mouse - NMR<br />	+	**[[1mse]], [[1msf]] – mTA DBD 90-193 + DNA – NMR - mouse<br />
-	**[[1mbe]], [[1mbf]] – mTA DBD repeat 1 + DNA - NMR<br />	+	**1mbe]], [[1mbf]] – mTA DBD repeat 1 + DNA - NMR<br />
-	**[[1mbg]], [[1mbh]] – mTA DBD repeat 2 + DNA - NMR<br />	+	**[1mbg]], [[1mbh]] – mTA DBD repeat 2 + DNA - NMR<br />
	**[[1mbj]], [[1mbk]] – mTA DBD repeat 3 + DNA - NMR<br />		**[[1mbj]], [[1mbk]] – mTA DBD repeat 3 + DNA - NMR<br />
-	**[[1h88]] – mTA DBD repeat 1,2,3 + DNA + CCAAT/enhancer binding protein β<br />	+	**[[1h88]] – mTA DBD + DNA + CCAAT/enhancer binding protein β<br />
-	**[[1h89]] – mTA DBD repeat 1,2,3 + DNA + CAAT/enhancer binding protein β<br />	+	**[[1h89]] – mTA DBD + DNA + CAAT/enhancer binding protein β<br />
	**[[1guu]] – mTA DBD repeat 1 <br />		**[[1guu]] – mTA DBD repeat 1 <br />
	**[[1gv2]] – mTA DBD repeat 2,3 <br />		**[[1gv2]] – mTA DBD repeat 2,3 <br />
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	**[[1gvd]] – mTA DBD repeat 2 (mutant) <br />		**[[1gvd]] – mTA DBD repeat 2 (mutant) <br />
	**[[1idy]], [[1idz]] – mTA DBD repeat 3 (mutant) - NMR<br />		**[[1idy]], [[1idz]] – mTA DBD repeat 3 (mutant) - NMR<br />
-	**[[1sb0]], [[2agh]] – mTA TAD + CREB-binding protein - NMR<br />	+	**[[1sb0]], [[2agh]] – mTA transcription activation domain + CREB-binding protein - NMR<br />
-	**[[2agh]] – mTA TAD + CREB-binding protein + HRX - NMR<br />	+	**[[6dmx]], [[6dnq]] – mTA transcription activation domain + CREB-binding protein p3ptide + Bzip factor <br />
-	**[[6dmx]], [[6dnq]] – mTA TAD + CREB-binding protein + BZIP factor <br />	+
-	*Psp operon transcriptional activator	+	*Psp operon TA
		+
		+	**[[2bjw]] – EcTA AAA domain – Escherichia coli<br />
-	**[[2bjw]] – EcTA AAA domain – ''Escherichia coli''<br />
-	**[[2bjv]], [[2c9c]], [[4qnm]] – EcTA AAA domain (mutant)<br />
-	**[[2c96]] – EcTA AAA domain + ATP<br />
	**[[4qnr]] – EcTA AAA domain (mutant) + ATP<br />		**[[4qnr]] – EcTA AAA domain (mutant) + ATP<br />
	**[[4qos]] – EcTA AAA domain (mutant) + ADP<br />		**[[4qos]] – EcTA AAA domain (mutant) + ADP<br />
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	**[[2c99]] – EcTA AAA domain + AMPPNP<br />		**[[2c99]] – EcTA AAA domain + AMPPNP<br />
	**[[2vii]] – EcTA AAA domain + AMP + Mg<br />		**[[2vii]] – EcTA AAA domain + AMP + Mg<br />
-	**[[5nss]] – EcTA AAA domain + RNAP subunits αββ'ω + DNA - Cryo EM<br />	+	**[[5nss]] – EcTA in RNA polymerase complex – Cryo EM<br />
-	*TenA transcriptional activator	+	*TenA TA
-	**[[1tyh]], [[1yaf]] – BsTA – ''Bacillus subtilis''<br />	+	**[[1tyh]], [[1yaf]] – BsTA – Bacillus subtilis<br />
-	**[[2qzc]] – TA – ''Sulfolobus solfataricus''<br />	+	**[[2qzc]] – TA – Sulfolobus solfataricus<br />
-	**[[3no6]] – TA – ''Staphylococcus epidermidis''<br />	+	**[[3no6]] – TA – Staphylococcus epidermidis<br />
	**[[1yak]] – BsTA + pyrimidine derivative<br />		**[[1yak]] – BsTA + pyrimidine derivative<br />
	**[[2qcx]] – BsTA (mutant) + pyrimidine derivative<br />		**[[2qcx]] – BsTA (mutant) + pyrimidine derivative<br />
-	**[[1udd]] – TA – ''Pyrococcus horikishii''<br />	+	**[[1udd]] – TA – Pyrococcus horikishii<br />
-	*LasR transcriptional activator or transcriptional regulator LasR	+	*LasR TA or transcriptional regulator LasR
-	**[[6mww]] – PaTA – ''Pseudomonas aeruginosa''<br />	+	**[[6mww]] – PaTA – Pseudomonas aeruginosa<br />
-	**[[2uv0]] – PaTA LBD residues 1-173<br />	+	**[[2uv0]] – PaTA LBD residues 1-173 <br />
	**[[3ix3]], [[6mvn]], [[6mvm]] – PaTA LBD + oxo-dodecanoyl-homoserine lactone<br />		**[[3ix3]], [[6mvn]], [[6mvm]] – PaTA LBD + oxo-dodecanoyl-homoserine lactone<br />
-	**[[3ix4]], [[3ix8]], [[3jpu]], [[6d6a]], [[6d6b]], [[6d6c]], [[6d6d]], [[6d6l]], [[6d6m]], [[6d6n]], [[6d6o]], [[6d6p]] – PaTA LBD + benzoate derivative<br />	+	**[[3ix4]], [[3ix8]], [[3jpu]], [[6d6a]], [[6d6b]], [[6d6c]], [[6d6d]], **[[6d6p]], [[6d6l]], [[6d6m]], [[6d6o]], [[6d6n]] – PaTA LBD + benzoate derivative<br />
	**[[6mwl]] – PaTA + oxothiolan derivative<br />		**[[6mwl]] – PaTA + oxothiolan derivative<br />
	**[[6mwh]] – PaTA + acetamide derivative<br />		**[[6mwh]] – PaTA + acetamide derivative<br />
	**[[4ng2]] – PaTA LBD + protein<br />		**[[4ng2]] – PaTA LBD + protein<br />
	**[[6mwz]] – PaTA (mutant) + peptide<br />		**[[6mwz]] – PaTA (mutant) + peptide<br />
		+	**[[6v7w]], [[6v7x]] – PaTA + Aqs1<br />
-	*CadC transcriptional activator; domains - DBD 1-107; periplasmic 188-512	+	*CadC TA
-	**[[3ly7]], [[3lya]] – EcTA periplasmic domain <br />	+	**[[3ly7]], [[3lya]] – EcTA periplasmic domain 188-512<br />
	**[[3ly8]], [[3ly9]] – EcTA periplasmic domain (mutant)<br />		**[[3ly8]], [[3ly9]] – EcTA periplasmic domain (mutant)<br />
-	**[[5ju7]] – EcTA DBD domain <br />	+	**[[5ju7]] – EcTA DBD 2-107<br />
-	*CynR transcriptional activator	+	*Mal-Rpel TA
-		+
-	**[[2hxr]] – EcTA LBD <br />	+
-	**[[3hfu]] – EcTA LBD + N3<br />	+
-		+
-	*Mal-Rpel transcriptional activator	+
	**[[2v51]], [[2v52]] – mTA residues 16-41 + actin <br />		**[[2v51]], [[2v52]] – mTA residues 16-41 + actin <br />
	**[[2yje]], [[2yjf]] – mTA Rpel domain + actin <br />		**[[2yje]], [[2yjf]] – mTA Rpel domain + actin <br />
-	*Brg1 transcriptional activator	+	Brg1 TA
-		+
-	**[[5ea1]] – hTA bromodomain - human<br />	+
-	**[[3uvd]] – hTA bromodomain + pyrrolidone derivative <br />	+
-	**[[5dkd]] – hTA bromodomain + pyridine derivative <br />	+
-		+
-	*VP30 transcriptional activator	+
		+	**[[5ea1]] – hTA bromodomain 1418-1536 - human<br />
		+	**[[3uvd]] – hTA bromodomain - NMR<br />
		+	**[[2grc]], [[3uvd]], [[5dkd]], [[6zs2]] – hTA bromodomain + inhibitor<br />
		+	**[[6hr2]] – hTA bromodomain + ElonginB + ElonginC + pVHL<br />
	**[[2i8b]] – TA C terminal – Zaire ebolavirus<br />		**[[2i8b]] – TA C terminal – Zaire ebolavirus<br />
	**[[3v7o]] – TA C terminal – Reston ebolavirus<br />		**[[3v7o]] – TA C terminal – Reston ebolavirus<br />
-	*TraR transcriptional activator
-	**[[1v4r]] – AtTA N-terminal - ''Streptomyces'' - NMR <br />	+	*Flagelar TA
-	**[[1l3l]] – AtTA + pheromone + DNA – ''Agrobacterium tumefaciens'' <br />	+
-	**[[1h0m]] – AtTA + auto-inducer + DNA <br />	+
-	**[[5w1s]] – EcTA + RNAP subunits αββ'ω + PROD + DNA <br />	+
-		+
-	*Flagelar transcriptional activator	+
	**[[1g8e]] – EcTA FlhD<br />		**[[1g8e]] – EcTA FlhD<br />
-	**[[2avu]] – EcTA FlhC+FlhD<br />	+	**[[2avu]] – EcTA FlhC+FLHD<br />
	**[[5hxg]] – StTA FlhD + STM1697 <br />		**[[5hxg]] – StTA FlhD + STM1697 <br />
-	*TipA transcriptional activator	+	*Tipa TA
-	**[[1ny9]] – SlTA antibiotic binding domain – ''Streptomyces lividans'' - NMR<br />	+	**[[1ny9]] – SlTA antibiotic binding domain – Streptomyces lividans - NMR<br />
	**[[2mbz]], [[2mc0]] - SlTA antibiotic binding domain + thiopeptide - NMR<br />		**[[2mbz]], [[2mc0]] - SlTA antibiotic binding domain + thiopeptide - NMR<br />
-	**[[2vz4]] – SlTA DBD + DNA<br />
-	*MtaN transcriptional activator
-	**[[1r8d]], [[1jbg]] – BsTA N-terminal <br />	+	**[[1r8d]] – BsTA <br />
-	**[[4p54]] – TA (mutant) - ''Helicobacter pylori'' <br />	+
-	*RfaH transcriptional activator	+	*Rfah TA
	**[[2oug]] – EcTA <br />		**[[2oug]] – EcTA <br />
	**[[2lcl]] – EcTA C terminal - NMR<br />		**[[2lcl]] – EcTA C terminal - NMR<br />
-	**[[5ond]] – EcTA (mutant) + DNA <br />	+	**[[5ond]] – EcTA + DNA <br />
-	*SoxR transcriptional activator	+	*SoxR TA or redox-sensitive transcriptional activator
	**[[2zhh]] – EcTA <br />		**[[2zhh]] – EcTA <br />
	**[[2zhg]] – EcTA + DNA<br />		**[[2zhg]] – EcTA + DNA<br />
		+	**[[6tf4]] – VcTA C terminal - Vibrio cholera - NMR<br />
-	*AmpR transcriptional activator	+	*GlxR TA
-	**[[3kos]] – CfTA effector binding domain – ''Citrobacter freundii''<br />	+	**[[3r6s]] – CgTA +cAMP – Corynebacterium glutamicum <br />
-	**[[3kot]] – CfTA effector binding domain (mutant)<br />	+	**[[4byy]] – CgTA <br />
-	**[[4wkm]] – CfTA effector binding domain + peptide<br />	+
-	**[[5mmh]] – PaTA effector binding domain<br />	+
-	*GlxR transcriptional activator	+	*OxyR TA or hydrogen peroxide-inducible genes activator
-	**[[4byy]] – CgTA – ''Corynebacterium glutamicum'' <br />	+	**[[3t22]], [[3ho7]], [[3uki]] – TA regulatory domain – Porphyromonas gingivalis <br />
-	**[[3r6s]], [[4cyd]] – CgTA + cAMP <br />	+	**[[7l4s]] – TA regulatory domain – Shewnella oneidensis<br />
		+	**[[4y0m]] – PaTA regulatory domain <br />
		+	**[[4x6g]], [[4xws]] – PaTA regulatory domain (mutant)<br />
		+	**[[1i69]], [[1i6a]] – EcTA regulatory domain (mutant)<br />
		+	**[[6g1d]] – CgTA regulatory domain (mutant)<br />
		+	**[[6g1b]], [[6g4r]] – CgTA regulatory domain + H2O2<br />
		+	**[[5x0v]] – VvTA - Vibrio vulnificus<br />
		+	**[[5b70]], [[5b7d]], [[5b7h]], [[5x0q]] – VvTA (mutant) <br />
		+	**[[3jv9]] – NmTA – Neisseria meningitidis <br />
-	*OxyR transcriptional activator	+	*PlcR TA
-	**[[3t22]], [[3ho7]], [[3uki]] – TA regulatory domain – ''Porphyromonas gingivalis'' <br />	+	**[[4fsc]] – BtTA - Bacillus thuringiensis <br />
-	**[[3jvt]] – TA – ''Neiserria meningitidis'' <br />	+	**[[2qfc]] – BtTA + PapR peptide <br />
-	**[[4x6g]] – PaTA (mutant) <br />	+	**[[3u3w]] – BtTA + DNA + PapR peptide <br />
-	**[[4y0m]] – PaTA regulatory domain <br />	+
-	**[[4xws]] – PaTA regulatory domain (mutant) <br />	+
-	**[[5x0v]] – VvTA-2 regulatory domain - ''Vibrio vulnificus'' <br />	+
-	**[[5x0q]], [[5b70]], [[5b7d]], [[5b7h]] – VvTA-2 regulatory domain (mutant)<br />	+
-	*PlcR transcriptional activator	+	*VirB TA or virulence regulon transcriptional activator VirB
-	**[[4fsc]] – BtTA - ''Bacillus thuringiensis'' <br />	+	**[[3vwb]], [[3w2a]], [[3w3c]] – TA core domain + DNA – Shigella flexneri<br />
-	**[[2qfc]] – BtTA + PAPR peptide <br />	+
-	**[[3u3w]] – BtTA + DNA + PAPR peptide <br />	+
-	*VirB transcriptional activator	+	*MafA TA
-		+
-	**[[3vwb]], [[3w2a]], [[3w3c]] – TA core domain + DNA – ''Shigella flexneri''<br />	+
-		+
-	*MafA transcriptional activator	+
	**[[4eot]] – hTA DBD<br />		**[[4eot]] – hTA DBD<br />
-	*CysB transcriptional activator	+	*CysB TA or Cys regulon transcriptional activator CysB
-	**[[4gwo]], [[4gxa]], [[4lon]], [[4lp2]] – StTA C terminal – ''Salmonella typhimurium''<br />	+	**[[4gwo]], [[4gxa]], [[4lon]], [[4lp2]] – StTA C terminal – Salmonella typhimurium<br />
	**[[4lq2]], [[4lq5]], [[4m4g]] – StTA C terminal + acetylserine<br />		**[[4lq2]], [[4lq5]], [[4m4g]] – StTA C terminal + acetylserine<br />
-	**[[1al3]] – TA cofactor binding domain – ''Klebsiella aerogenes''<br />	+	**[[1al3]] – TA cofactor binding domain – Klebsiella aerogenes<br />
	**[[5z50]] – PaTA regulatory domain <br />		**[[5z50]] – PaTA regulatory domain <br />
	**[[5z4y]], [[5z4z]] – PaTA NTD domain <br />		**[[5z4y]], [[5z4z]] – PaTA NTD domain <br />
-	*HlyU transcriptional activator	+	*HlyU TA
-	**[[4k2e]], [[4ooi]] – VcTA - ''Vibrio cholerae''<br />	+	**[[4k2e]], [[4ooi]] – VcTA <br />
-	**[[3jth]] – VvTA - ''Vibrio vulnificus'' <br />	+	**[[3jth]] – VvTA <br />
-	**[[5znx]] – VvTA + inhibitor<br />	+	**[[5znx]] – VvTA + inhibitor <br />
	*ToxR TA		*ToxR TA
	**[[6uue]], [[6utc]] – VvTA <br />		**[[6uue]], [[6utc]] – VvTA <br />
		+	**[[7nmb]], [[7nn6]] – VcTA - NMR<br />
	*LysR TA		*LysR TA
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	**[[5x0n]] – VvTA (mutant)<br />		**[[5x0n]] – VvTA (mutant)<br />
	**[[3t1b]], [[3szp]] – VcTA <br />		**[[3t1b]], [[3szp]] – VcTA <br />
-	**[[6yz3]] – PaTA <br />	+	**[[6tpr]], [[6z07]], [[6z17]], [[6z5k]], [[6yz3]], [[7o2t]], [[7o2u]] – PaTA + antagonist<br />
		+	**[[6yiz]], [[7nbw]] – PaTA + agonist<br />
	**[[5z7h]] – SaTA <br />		**[[5z7h]] – SaTA <br />
-	**[[4pzj]] – TA – ''Eggerthella lenta''<br />	+	**[[4pzj]] – TA – Eggerthella lenta<br />
-	**[[3hhf]] – NmTA – ''Neisseria meningitidis'' <br />	+	**[[3hhf]], [[3hhg]], [[4ab5]] – NmTA <br />
-	**[[3fzj]] – TA – ''Comamonas testosteroni''<br />	+	**[[3fzj]] – TA – Comamonas testosteroni<br />
		+	**[[1ixc]], [[1iz1]] – CnTA – Cupriavidus necator<br />
		+	**[[5xxp]], [[7d98]] – CnTA + DNA<br />
		+	**[[1uth]], [[2y7r]], [[5ae4]] – TA – Burkholderia cepacia<br />
		+	**[[7trv]], [[7trw]] – TA LBD – Yersinia pestis<br />
		+	**[[7erp]], [[7erq]] – CsTA regulatory domain – Cronobacter sakazakii<br />
		+	**[[7fdf]] – CsTA regulatory domain (mutant) <br />
-	*Aft2 transcriptional activator	+	*Aft2 TA
	**[[4lmg]] – yTA + DNA<br />		**[[4lmg]] – yTA + DNA<br />
-	*Cmpr transcriptional activator
-	**[[5z49]] – TA effector-binding domain + ribulose bisphosphate – ''Synechococcus elongatus''<br />	+	*Mga TA
-	*Mga transcriptional activator	+	**[[5way]] – SpTA – Streptococcus pneumoniae<br />
-	**[[5way]] – SpTA – ''Streptococcus pneumoniae''<br />
-	*RhaR transcriptional activator	+	*Spt7 TA
-		+
-	**[[5u9e]], [[5u93]] – TA regulatory domain – ''Bacteria latreille''<br />	+
-		+
-	*Spt7 transcriptional activator	+
	**[[6t9k]], [[6t9i]] – yTA in SAGA – Cryo EM<br />		**[[6t9k]], [[6t9i]] – yTA in SAGA – Cryo EM<br />
-	*Quorum-sensing TA	+	*Quorum-sensing TA or TraR
-	**[[5l07]] – YeTA – ''Yersinia enterocolitica''<br />	+	**[[5l07]] – YeTA – Yersinia enterocolitica<br />
	**[[5l09]] – YeTA + THF derivative<br />		**[[5l09]] – YeTA + THF derivative<br />
		+	**[[1l3l]] – AtTA + pheromone + DNA – Agrobacterium tumefaciens <br />
		+	**[[1h0m]] – AtTA + auto-inducer + DNA <br />
	*MexT TA		*MexT TA
Line 218:		Line 202:
	*ComR TA		*ComR TA
-	**[[5juf]] – TA – ''Streptococcus thermophilus''<br />	+	**[[5juf]], [[6qer]] – StTA – Streptococcus thermophilus<br />
-		+	**[[5jub]] – StTA + DNA<br />
-	*GabR TA	+	**[[5fd4]] – TA – Streptococcus suis<br />
-		+	**[[7n10]], [[7n1n]] – SmTA DBD + Prx – Streptococcus mutans<br />
-	**[[5t4k]], [[5t4j]], [[5t4l]] – BsTA EBO domain + pyridine derivative<br />	+	**[[6hu8]] – SvTA – Streptococcus vestibularis<br />
		+	**[[6hua]] – SvTA + peptide<br />
	*FasR TA		*FasR TA
-	**[[6o6p]] – MtTA + DNA – ''Mycobacterium tuberculosis''<br />	+	**[[6o6p]] – MtTA + DNA – Mycobacterium tuberculosis<br />
	**[[6o6o]] – MtTA + myristic acid<br />		**[[6o6o]] – MtTA + myristic acid<br />
		+	**[[6o6n]] – MtTA + arachinoyl-CoA<br />
-	*PrpR TA
-
-	**[[6d2s]], [[6cyj]], [[6cz6]], [[6cyy]] – MtTA <br />
-
-
-	*LrpC TA
-
-	**[[2cfx]] – BsTA <br />
	*ModE TA		*ModE TA
	**[[1o7l]], [[1h9s]] – EcTA + Mo <br />		**[[1o7l]], [[1h9s]] – EcTA + Mo <br />
-	**[[1b9m]], [[1b9n]] , [[1h9r]]– EcTA + Ni <br />	+	**[[1b9m]], [[1b9n]], [[1h9r]] – EcTA + Ni <br />
-		+
-	*RutR TA	+
-		+
-	**[[4x1e]] – EcTA <br />	+
-	**[[4xk4]], [[4jyk]] – EcTA + uracil derivative<br />	+
	*TetR family TA		*TetR family TA
-	**[[1z77]], [[2id6]], [[2iek]], [[1zkg]], [[4i76]], [[3ih2]], [[3ih3]], [[3ih4]] – TmTA – ''Thermotoga maritima''<br />	+	**[[1z77]], [[2id6]], [[2iek]], [[1zkg]], [[4i76]], [[3ih2]], [[3ih3]], [[3ih4]] – TmTA – Thermotoga maritima<br />
	**[[4i6z]] – TmTA + DNA<br />		**[[4i6z]] – TmTA + DNA<br />
-	**[[1zk8]], [[2fq4]], [[4me9]] – BcTA – ''Bacillus cereus''<br />	+	**[[1zk8]], [[2fq4]], [[4me9]] – BcTA – Bacillus cereus<br />
-	**[[3cwr]] – TA – ''Rhodspirillum rubrum''<br />	+	**[[3cwr]] – TA – Rhodspirillum rubrum<br />
-	**[[1z0x]] – EfTA – ''Enterococcus faecalis''<br />	+	**[[1z0x]] – EfTA – Enterococcus faecalis<br />
-	**[[3vuq]] – TtTA – ''Thermus thermophilus''<br />	+	**[[3c2b]] – AfTA – Agrobacterium fabrum<br />
-	**[[3c2b]] – AfTA – ''Agrobacterium fabrum''<br />	+
	**[[2o7t]] – CgTA <br />		**[[2o7t]] – CgTA <br />
	**[[2g7s]] – AtTA <br />		**[[2g7s]] – AtTA <br />
-	**[[5d19]] – MtTA <br />	+	**[[3gzi]] – TA – Shewanella loihica<br />
-	**[[3gzi]] – TA – ''Shewanella loihica''<br />	+	**[[2qib]], [[2zcx]], [[6srm]] – ScTA – Streptomyces coelicolor<br />
-	**[[3dcf]] – TA – ''Thermobifida fusca''<br />	+	**[[2hyt]] – TA – Pectobacterium atrosepticum<br />
-	**[[2qib]], [[2zcx]], [[7ky1]] – TA – ''Streptomyces coelicolor''<br />	+	**[[3cdl]] – PsTA – Pseudomonas syringae<br />
-	**[[2hyt]] – TA – ''Pectobacterium atrosepticum''<br />	+	**[[3kkc]] – SaTA – Streptococcus agalactiae<br />
-	**[[3cdl]] – PsTA – ''Pseudomonas syringae''<br />	+	**[[3nnr]] – TA – Marinobacter aquaeolei<br />
-	**[[3kkc]] – TA – ''Streptococcus agalactiae''<br />	+	**[[3on4]] – TA – Legionella pneumophila<br />
-	**[[3mvp]] – TA – ''Streptococcus mutans''<br />	+	**[[3f1b]] – RjTA – Rhodococcus jostii<br />
-	**[[3nnr]] – TA – ''Marinobacter aquaeolei''<br />	+	**[[3eup]] – TA – Cytophaga hutchinsonii<br />
-	**[[3on4]] – TA – ''Legionella pneumophila''<br />	+	**[[3egq]] – TA – Archaeoglobus fulgidus<br />
-	**[[2eh3]] – TA – ''Aquifex aeolicus''<br />	+	**[[4hku]] – LmTA – Listeria monocytogenes<br />
-	**[[3f1b]] – RjTA – ''Rhodococcus jostii''<br />	+	**[[3nrg]], [[3qbm]] – TA – Chlotoflexus aurantiacus<br />
-	**[[3eup]] – TA – ''Cytophaga hutchinsonii''<br />	+
-	**[[3egq]] – TA – ''Archaeoglobus fulgidus''<br />	+
-	**[[4hku]] – TA – ''Listeria monocytogenes''<br />	+
-	**[[3nrg]], [[3qbm]] – TA – ''Chlotoflexus aurantiacus''<br />	+
-	**[[6g87]] – BdTA – ''Bradyrhizobium diazoefficiens''<br />	+
-	**[[6g8h]] – BdTA + naringenin <br />	+
-	**[[6g8g]] – BdTA + genistein <br />	+
	**[[6nsr]] – PaTA (mutant) + DNA<br />		**[[6nsr]] – PaTA (mutant) + DNA<br />
-	**[[4jkz]] – MsTA – ''Mycobacterium smegmatis''<br />	+	**[[4jkz]] – MsTA – Mycobacterium smegmatis<br />
-	**[[6el2]] – SacTA – ''Sulfolobus acidocaldarius''<br />	+	**[[6el2]] – SacTA – Sulfolobus acidocaldarius<br />
	**[[6en8]] – SacTA + DNA<br />		**[[6en8]] – SacTA + DNA<br />
		+
		+	*TetR/AcrR family TA
		+
		+	**[[2rae]] – RjTA <br />
		+	**[[3lhq]] – StTA <br />
		+	**[[3b81]] – CpTA – Clostridium acetobutylicum<br />
		+	**[[3dcf]] – TA – Thermobifida fusca<br />
		+	**[[3mvp]] – SmTA <br />
		+	**[[5d18]], [[5d19]], [[6a4l]], [[6a4w]] – MtTA <br />
		+	**[[2eh3]] – TA – Aquifex aeolicus<br />
		+	**[[3vuq]] – TtTA – Thermus thermophilus<br />
		+	**[[7eqe]] – SgTA – Streptococcus griseus<br />
		+	**[[7eqf]] – SgTA + ligand<br />
		+	**[[5gp9]], [[5gpa]] – BhTA – Bacillus halodurans<br />
		+	**[[5gpc]] – BhTA + DNA <br />
		+	**[[6g87]] – BdTA – Bradyrhizobium diazoefficiens<br />
		+	**[[6g8h]] – BdTA + naringenin <br />
		+	**[[6g8g]] – BdTA + genistein <br />
	*GntR family TA		*GntR family TA
Line 287:		Line 270:
	**[[3l5z]] – BcTA <br />		**[[3l5z]] – BcTA <br />
	**[[3ddv]] – EfTA <br />		**[[3ddv]] – EfTA <br />
-	**[[3sxy]] – TmTA <br />	+	**[[3fms]], [[3sxy]] – TmTA <br />
	**[[3c7j]] – PsTA <br />		**[[3c7j]] – PsTA <br />
-	**[[2p19]] – CgTA <br />	+	**[[2di3]], [[2p19]] – CgTA <br />
-	**[[3tqn]] – TA – ''Coxiella burnetii''<br />	+	**[[3tqn]] – TA – Coxiella burnetii<br />
		+	**[[6za0]], [[6za3]], [[7za7]] – AfTA <br />
		+	**[[6z74]], [[6zab]] – AfTA + DNA<br />
		+	**[[7u5q]] – TA – Brucella melitensis<br />
		+	**[[6sbs]] – SacTA <br />
		+	**[[3h5o]] – TA – Chromobacterium violaceum <br />
		+	**[[6az6]], [[7b5t]], [[7b5y]], [[7b5w]] – SaTA <br />
		+	**[[7b5u]] – SaTA + diAMP <br />
		+	**[[7oz3]] – SaTA + DNA – Cryo EM<br />
		+	**[[4r1h]] – LmTA <br />
		+	**[[3ihu]] – TA – Ralstonia eutropha <br />
		+	**[[3lhe]] – TA – Bacillus anthracis <br />
		+	**[[3f8m]] – MsTA <br />
-	*MarR family TA	+	*MarR family TA or multiple antibiotic resistance protein
-	**[[3boq]], [[3cjn]], [[3e6m]] – RpTA - ''Ruegeria pomeryi''<br />	+	**[[3boq]], [[3cjn]], [[3e6m]] – RpTA - Ruegeria pomeryi<br />
-	**[[3s2w]] – TA – ''Methanosarcina mazei'' <br />	+	**[[3s2w]] – TA – Methanosarcina mazei <br />
-	**[[2fbk]] – DrTA – ''Deinococcus radiodurans''<br />	+	**[[3bpv]] – TA – Methanobacterium thermoautotrophicum <br />
		+	**[[2fbk]] – DrTA – Deinococcus radiodurans<br />
	**[[5dd8]] – DrTA (mutant) <br />		**[[5dd8]] – DrTA (mutant) <br />
-	**[[2fa5]] – TA – ''Xanthomonas campestris''<br />	+	**[[2fa5]] – TA – Xanthomonas campestris<br />
-	**[[5aiq]] – NmTA <br />	+	**[[3g3z]], [[5aiq]] – NmTA <br />
	**[[5aip]] – NmTA + hydroxyphenylacetate <br />		**[[5aip]] – NmTA + hydroxyphenylacetate <br />
-	**[[5e1w]] – DmTA – ''Dihalococcoides mccartyi''<br />	+	**[[5e1w]] – DmTA – Dihalococcoides mccartyi<br />
	**[[5e1z]], [[5e1x]], [[5e20]] – DmTA + phenol derivative <br />		**[[5e1z]], [[5e1x]], [[5e20]] – DmTA + phenol derivative <br />
-	**[[6c28]] – TA + coumaroyl-CoA – ''Rhodopseudomonas palustris'' <br />	+	**[[6c28]] – RpTA + coumaroyl-CoA – Rhodopseudomonas palustris <br />
	**[[3fm5]] – RjTA <br />		**[[3fm5]] – RjTA <br />
	**[[1z91]] – BsTA <br />		**[[1z91]] – BsTA <br />
		+	**[[4b8x]] – ScTA <br />
		+	**[[4yif]] – MtTA <br />
		+	**[[3vb2]], [[3voe]], [[4jba]] – EcTA <br />
		+	**[[3vod]] – EcTA (mutant)<br />
		+	**[[5h3r]] – EcTA (mutant) + DNA<br />
		+	**[[5eri]] – CdTA – Clostridium difficile<br />
		+	**[[7dvn]] – TA + effector – Paenisporosarcina<br />
		+	**[[3u2r]] – TA – Planctopirus limnophilus<br />
		+	**[[2rdp]] – TA – Bacillus stearothermophilus<br />
-	*MerR family TA	+	*MerR family TA or mercuric resistance operon regulatory protein
	**[[3hh0]] – BcTA <br />		**[[3hh0]] – BcTA <br />
	**[[3gpv]] – BtTA <br />		**[[3gpv]] – BtTA <br />
		+	**[[4ua1]], [[4ua2]] – TA – Bacillus megaterium<br />
		+	**[[5crl]] – PaTA <br />
		+	**[[5gpe]] – TA – Cupriavidus metallidurans<br />
		+	**[[3cnb]] – TA – Colwellia psychrerythraea <br />
		+	**[[6d90]] – HiTA – Haemophilia influenzae<br />
		+	**[[5d8c]] – HiTA + DNA <br />
		+	**[[6xl6]], [[6xla]], [[6xlk]] – EcTA + DNA – Cryo EM<br />
		+	**[[6xl5]], [[6xl9]], [[6xlj]] – EcTA in RNP complex – Cryo EM<br />
	*AsnC family TA		*AsnC family TA
	**[[3i4p]] – AfTA <br />		**[[3i4p]] – AfTA <br />
		+	**[[2cg4]] – EcTA <br />
-	*AraC family TA	+	*AraC family TA or arabinose operon regulatory protein
-	**[[3gra]] – PpTA – ''Pseudomonas putida''<br />	+	**[[3gra]] – PpTA – Pseudomonas putida<br />
-	**[[3cu5]] – TA – ''Lacnoclostridium phytofermentans''<br />	+	**[[3cu5]] – TA – Lacnoclostridium phytofermentans<br />
	**[[5chh]] – PaTA <br />		**[[5chh]] – PaTA <br />
		+	**[[2ara]] – EcTA <br />
		+	**[[1xja]] – EcTA dimerization domain (mutant)<br />
		+	**[[2k9s]] – EcTA DBD - NMR<br />
		+	**[[2arc]] – EcTA + arabinose<br />
		+	**[[2aac]] – EcTA + fucose<br />
	*LacI family TA		*LacI family TA
	**[[3kjx]], [[3e3m]] – RpTA <br />		**[[3kjx]], [[3e3m]] – RpTA <br />
-	**[[3jy6]] – TA - ''Lactobacillus brevis'' <br />	+	**[[3jy6]] – TA - Lactobacillus brevis <br />
-	**[[6chk]] – LcTA - ''Lactobacillus casei'' <br />	+	**[[6chk]] – LcTA - Lactobacillus casei <br />
	**[[4rk5]], [[4rk4]] – LcTA + sugar <br />		**[[4rk5]], [[4rk4]] – LcTA + sugar <br />
	**[[4rk0]], [[4rk1]] – EfTA + ribose<br />		**[[4rk0]], [[4rk1]] – EfTA + ribose<br />
	**[[3h5t]] – CgTA <br />		**[[3h5t]] – CgTA <br />
	**[[3kke]] – MsTA <br />		**[[3kke]] – MsTA <br />
-	**[[4rkq]], [[4rkr]] – TA - ''Arthrobacter''<br />	+	**[[4rkq]], [[4rkr]] – TA - Arthrobacter<br />
	*PadR family TA		*PadR family TA
Line 337:		Line 356:
	**[[5zhv]], [[5zi8]], [[5zhc]] – MtTA <br />		**[[5zhv]], [[5zi8]], [[5zhc]] – MtTA <br />
	**[[5zqh]] – SpTA <br />		**[[5zqh]] – SpTA <br />
-	**[[5x12]] – BsTA <br />	+	**[[5x12]], [[7cbv]] – BsTA <br />
-	**[[5y8t]] – BsTA + coumaric acid<br />	+	**[[5x13]], [[5y8t]] – BsTA + coumaric acid<br />
		+	**[[5x14]] – BsTA + ferulic acid<br />
		+	**[[6abq]], [[6abt]] – LmTA <br />
		+	**[[5dym]] – CdTA <br />
-	*TrmB TA	+	*TrmB TA or tRNA (guanine-N(7)-) methyltransferase
	**[[2f5t]] – TA – Thermococcus litoralis<br />		**[[2f5t]] – TA – Thermococcus litoralis<br />
		+	**[[3qph]] – PfTA + sucrose – Pyrococcus furiosus<br />
	*IclR TA		*IclR TA
	**[[1mkm]] – TmTA <br />		**[[1mkm]] – TmTA <br />
		+	**[[2o99]], [[2o9a]] – EcTA C-terminal <br />
		+	**[[1td5]] – EcTA LBD <br />
		+	**[[7cuo]] – TA + hydroxybenzoate – Microbacterium hydrocarbonoxydans <br />
	*BgaR TA		*BgaR TA
-	**[[6nwo]] – CpTA – ''Clostridium perfringens''<br />	+	**[[6nwo]] – CpTA – Clostridium perfringens<br />
	**[[6nx3]], [[6nwj]], [[6nwm]], [[6nwh]] – CpTA + pyranose derivative<br />		**[[6nx3]], [[6nwj]], [[6nwm]], [[6nwh]] – CpTA + pyranose derivative<br />
Line 361:		Line 387:
	**[[4aij]], [[4aik]] – YpTA + DNA <br />		**[[4aij]], [[4aik]] – YpTA + DNA <br />
-	*BenM TA
-
-	**[[3k1n]] – AbTA – ''Acinetobacter baylyi''<br />
-	**[[3k1p]] – AbTA (mutant)<br />
-	**[[2f6g]], [[2f6p]], [[2f97]] – AbTA effector-binding domain 81-304<br />
-	**[[3m1e]] – AbTA DBD 1-87<br />
-	**[[4ihs]], [[4iht]] – AbTA effector-binding domain + DNA <br />
-	**[[2f78]], [[2f7a]], [[2f7c]] – AbTA effector-binding domain + effector <br />
-	**[[2h9b]] – EfTA (mutant)<br />
-
-	*CatM TA
-
-	**[[2f7b]], [[2h98]] – AbTA effector-binding domain <br />
	*CouR TA		*CouR TA
-	**[[5cyv]] – RjTA + coumaroyl-CoA – ''Rhodococcus jostii''<br />	+	**[[5cyv]], [[6c28]] – RjTA + coumaroyl-CoA – Rhodococcus jostii<br />
		+	**[[6c9t]] – RpTA <br />
		+	**[[6c2s]] – RpTA + DNA <br />
-	*MgrA TA
-
-	**[[2bv6]] – SaTA – ''Staphylococcus aureus''<br />
-
-	*SarX TA
-
-	**[[5hs5]], [[5ywj]], [[6k8e]] – SaTA <br />
-
-	*QacR TA
-
-	**[[2gby]] – SaTA <br />
-	**[[3br6]] – SaTA (mutant) + rhodamine<br />
-	**[[3bqz]] – SaTA + malachite green<br />
-	**[[3br1]], [[3br2]] – SaTA (mutant) + dequalinium<br />
-	**[[2g0e]] – TA + drug – ''Staphylococcus haemolyticus''<br />
-
-	*AcrR TA
-
-	**[[2qop]] – EcTA <br />
	*CueR TA		*CueR TA
	**[[1q07]], [[1q06]], [[1q05]] – EcTA <br />		**[[1q07]], [[1q06]], [[1q05]] – EcTA <br />
-
-	*PurR TA
-
-	**[[3d8u]] – VpTA – ''Vibrio parahaemolyticus''<br />
	*LuxR TA		*LuxR TA
Line 414:		Line 406:
	*LuxT TA		*LuxT TA
-	**[[3ljl]] – VpTA <br />	+	**[[3b4s]], [[3ljl]] – VpTA <br />
-	*ClgR TA	+	*ClgR TA or Clp gene regulator
	**[[5woq]] – MsTA <br />		**[[5woq]] – MsTA <br />
		+	**[[3f51]], [[3f52]] – CgTA <br />
	*LmrR TA		*LmrR TA
-	**[[3f8b]], [[6i8n]] – LlTA – ''Lactococcus lactis''<br />	+	**[[3f8b]], [[6i8n]] – LlTA – Lactococcus lactis<br />
	**[[3f8c]], [[3f8f]] – LlTA + drug<br />		**[[3f8c]], [[3f8f]] – LlTA + drug<br />
	**[[6vwe]], [[6do0]] – LlTA + Rh complex<br />		**[[6vwe]], [[6do0]] – LlTA + Rh complex<br />
	**[[6r1l]] – LlTA + Cu + phenanthroline<br />		**[[6r1l]] – LlTA + Cu + phenanthroline<br />
		+	**[[4zzd] – LlTA + riboflavine<br />
		+	**[[6fuu]] – LlTA + heme<br />
	*MvfR TA		*MvfR TA
-	**[[6z17]] – PaTA <br />	+	**[[4jvc]], [[6z17]] – PaTA <br />
-	**[[6z5k]] – PaTA + inhibitor<br />	+	**[[4jvd]], [[4jvi]], [[6q7u]], [[6q7v]], [[6tpr]], [[6yiz]], [[6yz3]], [[6z07]], **[[6z17]], [[6z5k]], [[7nbw]], [[7o2t]], [[7o2u]] – PaTA + inhibitor<br />
		+	**[[6b8a]], [[6q7w]] – PaTA LBD 94-295 + inhibitor<br />
	*HdfR TA		*HdfR TA
-	**[[6wn5]] – TA – ''Klebsiella pneumoniae''<br />	+	**[[6wn5]] – TA – Klebsiella pneumoniae<br />
	*McbR TA		*McbR TA
	**[[4p9f]] – EcTA <br />		**[[4p9f]] – EcTA <br />
		+	**[[4ab5]] – MnTA <br />
		+	**[[4ab6]] – MnTA (mutant)<br />
	*MetR TA		*MetR TA
Line 444:		Line 442:
	**[[5fo5]] – EcTA DBD<br />		**[[5fo5]] – EcTA DBD<br />
-	*McbR TA	+	*YvhJ TA
	**[[3nxh]] – BsTA <br />		**[[3nxh]] – BsTA <br />
Line 450:		Line 448:
	*CgmR TA		*CgmR TA
-	**[[2zoy]] – CgTA <br />	+	**[[2yve]], [[2zoy]] – CgTA <br />
	**[[2zoz]] – CgTA + ethidium<br />		**[[2zoz]] – CgTA + ethidium<br />
		+	**[[2yvh]] – CgTA + DNA<br />
-	*AraR TA	+	*AraR TA or arabinose metabolism transcriptional repressor
-	**[[5bs6]] – TA – ''Bacterioides thetaiotaomicron''<br />	+	**[[5bs6]], [[5dd4]] – BtTA – Bacterioides thetaiotaomicron<br />
		+	**[[3tb6]] – BtTA effector-binding domain 71-362 + arabinose<br />
		+	**[[5ddg]] – BtTA + DNA<br />
		+	**[[5deq]] – BtTA 1-225 + arabinose<br />
		+	**[[4egy]], [[4egz]], [[4h0e]], [[5d4r]], [[5d4s]] – BsTA DBD 1-68 + DNA<br />
-	*CarH TA	+	*CarH TA or light-dependent transcriptional regulator
-	**[[5c8d]] – TtTA + adnosylcobalamin<br />	+	**[[5c8a]], [[5c8d]], [[5c8e]], [[5c8f]] – TtTA + cobalamin derivative<br />
-	*ZitR TA	+	*ZitR TA or zinc transport transcriptional regulator
-	**[[5yhy]], [[5yi0]], [[5yi1]] – LlTA (mutant)<br />	+	**[[5yhx]] – LlTA <br />
		+	**[[5yhy]], [[5yhz]], [[5yi0]], [[5yi1]], [[6fi9]] – LlTA (mutant)<br />
		+	**[[5yi2]] – LlTA + DNA<br />
		+	**[[5yi3]] – LlTA (mutant) + DNA<br />
	*LsrR TA		*LsrR TA
Line 470:		Line 476:
	**[[4l4z]], [[4l50]], [[4l51]], [[4l5i]], [[4l5j]] – EcTA + ligand<br />		**[[4l4z]], [[4l50]], [[4l51]], [[4l5i]], [[4l5j]] – EcTA + ligand<br />
-	*HTH-type TA	+	*HTH-type TA or helix-turn-helix-type
	**[[2uxu]] – PpTA TtgR + naringenin<br />		**[[2uxu]] – PpTA TtgR + naringenin<br />
Line 476:		Line 482:
	**[[2uxi]] – PpTA TtgR + phloretin<br />		**[[2uxi]] – PpTA TtgR + phloretin<br />
	**[[6ugl]], [[6kju]] – VcTA + pyrazine derivative<br />		**[[6ugl]], [[6kju]] – VcTA + pyrazine derivative<br />
		+	**[[2bv6]] – SaTA MgrA – Staphylococcus aureus<br />
		+	**[[5hs5]], [[5ywj]], [[6k8e]] – SaTA SarX<br />
	**[[3hrm]], [[3hse]] – SaTA SarZ <br />		**[[3hrm]], [[3hse]] – SaTA SarZ <br />
	**[[6r1p]] – MtTA EthR <br />		**[[6r1p]] – MtTA EthR <br />
	**[[1ysq]] – EcTA YiaJ <br />		**[[1ysq]] – EcTA YiaJ <br />
		+	**[[2qop]], [[3bcg]] – EcTA AcrR<br />
		+	**[[6ldi]], [[6xh7]], [[6xh8]], [[7c17]] – EcTA CueR in transcription activation complex – Cryo EM <br />
		+	**[[4wls]], [[4wlw]] – EcTA CueR + DNA<br />
		+	**[[4x1e]] – EcTA RutR<br />
		+	**[[4xk4]], [[4jyk]] – EcTA RutR + uracil derivative<br />
		+	**[[2hxr]] – EcTA CynR LBD <br />
		+	**[[3hfu]] – EcTA CynR LBD + N3<br />
	**[[2gfn]] – RjTA Rha1 <br />		**[[2gfn]] – RjTA Rha1 <br />
-	**[[1i1g]] – TA LrpA – ''Pyrococcus furiosus''<br />	+	**[[1i1g]] – PfTA LrpA <br />
-	**[[7cla]] – TA SkgA – ''Caulobacter vibrioides''<br />	+	**[[7cla]] – TA SkgA – Caulobacter vibrioides<br />
		+	**[[7bzd]] – BsTA HxlR <br />
		+	**[[7bze]] – BsTA HxlR (mutant)<br />
		+	**[[7bzg]] – BsTA HxlR + DNA<br />
		+	**[[7amn]], [[7amt]] – TA LuxR + DNA – Vibrio alginolyticus<br />
		+	**[[2dtz]], [[2hq5]] – SaTA QacR (mutant)<br />
		+	**[[3bqz]], [[3br0]], [[3btc]], [[3btl]] – SaTA QacR (mutant) + malachite green<br />
		+	**[[3br1]], [[3br2]], [[3bt9]], [[3btj]] – SaTA QacR (mutant) + dequalinium<br />
		+	**[[3bti]] – SaTA QacR (mutant) + berberine<br />
		+	**[[1qvu]],[[3br3]], [[3pm1]] – SaTA QacR (mutant) + ethidium<br />
		+	**[[1rkw]], [[1rpw]] – SaTA QacR (mutant) + pentamadine<br />
		+	**[[1qvt]] – SaTA QacR (mutant) + proflavine<br />
		+	**[[3br5]], [[3br6]] – SaTA QacR (mutant) + rhodamine<br />
		+	**[[2gby]] – SaTA QacR (mutant) + berenil<br />
		+	**[[2g0e]] – SaTA QacR (mutant) + drug<br />
		+	**[[3k1n]] – AbTA BenM – Acinetobacter baylyi<br />
		+	**[[3k1p]] – AbTA BenM (mutant)<br />
		+	**[[2f6g]], [[2f6p]], [[2f97]] – AbTA BenM effector-binding domain 81-304<br />
		+	**[[3m1e]] – AbTA BenM DBD 1-87<br />
		+	**[[4ihs]], [[4iht]] – AbTA BenM effector-binding domain + DNA <br />
		+	**[[2f78]], [[2f7a]], [[2f7c]] – AbTA BenM effector-binding domain + effector <br />
		+	**[[2h9b]] – EfTA BenM (mutant)<br />
		+	**[[2f7b]], [[2h98]] – AbTA CatM effector-binding domain <br />
		+	**[[3glb]] – AbTA CatM effector-binding domain (mutant)<br />
		+	**[[2f7c]] – AbTA CatM effector-binding domain + muconate<br />
		+	**[[2cfx]] – BsTA LrpC<br />
		+	**[[2gqq]] – EcTA LrpC<br />
		+	**[[6d2s]], [[6cyj]], [[6cz6]], [[6cyy]] – MtTA PrpR<br />
		+	**[[2pju]] – EcTA PrpR<br />
		+	**[[5t4k]], [[5t4j]], [[5t4l]], [[5x03]] – BsTA GabR EBO domain + pyridine derivative<br />
		+	**[[4mgr]], [[4nob]], [[4tv7]] – BsTA GabR <br />
		+	**[[6uxz]] – BsTA GabR + agonist<br />
		+	**[[5u9e]], [[5u93]] – TA RhaR regulatory domain – Bacteria latreille<br />
		+	**[[5z49]] – TA CmpR effector-binding domain + ribulose bisphosphate – Synechococcus elongatus<br />
		+	**[[3kos]] – CfTA AmpR effector binding domain – Citrobacter freundii<br />
		+	**[[3kot]] – CfTA AmpR effector binding domain (mutant)<br />
		+	**[[4wkm]] – CfTA AmpR effector binding domain + peptide<br />
		+	**[[5mmh]] – PaTA AmpR effector binding domain <br />

---

Revision as of 10:12, 4 May 2022

3D Structures of transcriptional activator

Updated on 04-May-2022 - For a general description of the protein see Transcriptional activator {{#tree:id=OrganizedByTopic|openlevels=0|

• Gcn4 TA See Gcn4

• Gcn5 TA

• • 1e6i – yTA brododomain + histone H4 peptide - yeast
    
  • 1ygh – yTA histone acetyltransferase domain
    

• C-Myb TA; domains – DBD ; DBD repeat 1 38-89; repeat 2 90-141; repeat 3 142-193; transcription activation 291-315

• • 1mse, 1msf – mTA DBD 90-193 + DNA – NMR - mouse
    
  • 1mbe]], 1mbf – mTA DBD repeat 1 + DNA - NMR
    
  • [1mbg]], 1mbh – mTA DBD repeat 2 + DNA - NMR
    
  • 1mbj, 1mbk – mTA DBD repeat 3 + DNA - NMR
    
  • 1h88 – mTA DBD + DNA + CCAAT/enhancer binding protein β
    
  • 1h89 – mTA DBD + DNA + CAAT/enhancer binding protein β
    
  • 1guu – mTA DBD repeat 1
    
  • 1gv2 – mTA DBD repeat 2,3
    
  • 1gv5 – mTA DBD repeat 2
    
  • 1gvd – mTA DBD repeat 2 (mutant)
    
  • 1idy, 1idz – mTA DBD repeat 3 (mutant) - NMR
    
  • 1sb0, 2agh – mTA transcription activation domain + CREB-binding protein - NMR
    
  • 6dmx, 6dnq – mTA transcription activation domain + CREB-binding protein p3ptide + Bzip factor
    

• Psp operon TA

• • 2bjw – EcTA AAA domain – Escherichia coli
    

• • 4qnr – EcTA AAA domain (mutant) + ATP
    
  • 4qos – EcTA AAA domain (mutant) + ADP
    
  • 2c98 – EcTA AAA domain + ADP
    
  • 2c99 – EcTA AAA domain + AMPPNP
    
  • 2vii – EcTA AAA domain + AMP + Mg
    
  • 5nss – EcTA in RNA polymerase complex – Cryo EM
    

• TenA TA

• • 1tyh, 1yaf – BsTA – Bacillus subtilis
    
  • 2qzc – TA – Sulfolobus solfataricus
    
  • 3no6 – TA – Staphylococcus epidermidis
    
  • 1yak – BsTA + pyrimidine derivative
    
  • 2qcx – BsTA (mutant) + pyrimidine derivative
    
  • 1udd – TA – Pyrococcus horikishii
    

• LasR TA or transcriptional regulator LasR

• • 6mww – PaTA – Pseudomonas aeruginosa
    
  • 2uv0 – PaTA LBD residues 1-173
    
  • 3ix3, 6mvn, 6mvm – PaTA LBD + oxo-dodecanoyl-homoserine lactone
    
  • 3ix4, 3ix8, 3jpu, 6d6a, 6d6b, 6d6c, 6d6d, **6d6p, 6d6l, 6d6m, 6d6o, 6d6n – PaTA LBD + benzoate derivative
    
  • 6mwl – PaTA + oxothiolan derivative
    
  • 6mwh – PaTA + acetamide derivative
    
  • 4ng2 – PaTA LBD + protein
    
  • 6mwz – PaTA (mutant) + peptide
    
  • 6v7w, 6v7x – PaTA + Aqs1
    

• CadC TA

• • 3ly7, 3lya – EcTA periplasmic domain 188-512
    
  • 3ly8, 3ly9 – EcTA periplasmic domain (mutant)
    
  • 5ju7 – EcTA DBD 2-107
    

• Mal-Rpel TA

• • 2v51, 2v52 – mTA residues 16-41 + actin
    
  • 2yje, 2yjf – mTA Rpel domain + actin
    

Brg1 TA

• • 5ea1 – hTA bromodomain 1418-1536 - human
    
  • 3uvd – hTA bromodomain - NMR
    
  • 2grc, 3uvd, 5dkd, 6zs2 – hTA bromodomain + inhibitor
    
  • 6hr2 – hTA bromodomain + ElonginB + ElonginC + pVHL
    
  • 2i8b – TA C terminal – Zaire ebolavirus
    
  • 3v7o – TA C terminal – Reston ebolavirus
    

• Flagelar TA

• • 1g8e – EcTA FlhD
    
  • 2avu – EcTA FlhC+FLHD
    
  • 5hxg – StTA FlhD + STM1697
    

• Tipa TA

• • 1ny9 – SlTA antibiotic binding domain – Streptomyces lividans - NMR
    
  • 2mbz, 2mc0 - SlTA antibiotic binding domain + thiopeptide - NMR
    

• • 1r8d – BsTA
    

• Rfah TA

• • 2oug – EcTA
    
  • 2lcl – EcTA C terminal - NMR
    
  • 5ond – EcTA + DNA
    

• SoxR TA or redox-sensitive transcriptional activator

• • 2zhh – EcTA
    
  • 2zhg – EcTA + DNA
    
  • 6tf4 – VcTA C terminal - Vibrio cholera - NMR
    

• GlxR TA

• • 3r6s – CgTA +cAMP – Corynebacterium glutamicum
    
  • 4byy – CgTA
    

• OxyR TA or hydrogen peroxide-inducible genes activator

• • 3t22, 3ho7, 3uki – TA regulatory domain – Porphyromonas gingivalis
    
  • 7l4s – TA regulatory domain – Shewnella oneidensis
    
  • 4y0m – PaTA regulatory domain
    
  • 4x6g, 4xws – PaTA regulatory domain (mutant)
    
  • 1i69, 1i6a – EcTA regulatory domain (mutant)
    
  • 6g1d – CgTA regulatory domain (mutant)
    
  • 6g1b, 6g4r – CgTA regulatory domain + H2O2
    
  • 5x0v – VvTA - Vibrio vulnificus
    
  • 5b70, 5b7d, 5b7h, 5x0q – VvTA (mutant)
    
  • 3jv9 – NmTA – Neisseria meningitidis
    

• PlcR TA

• • 4fsc – BtTA - Bacillus thuringiensis
    
  • 2qfc – BtTA + PapR peptide
    
  • 3u3w – BtTA + DNA + PapR peptide
    

• VirB TA or virulence regulon transcriptional activator VirB

• • 3vwb, 3w2a, 3w3c – TA core domain + DNA – Shigella flexneri
    

• MafA TA

• • 4eot – hTA DBD
    

• CysB TA or Cys regulon transcriptional activator CysB

• • 4gwo, 4gxa, 4lon, 4lp2 – StTA C terminal – Salmonella typhimurium
    
  • 4lq2, 4lq5, 4m4g – StTA C terminal + acetylserine
    
  • 1al3 – TA cofactor binding domain – Klebsiella aerogenes
    
  • 5z50 – PaTA regulatory domain
    
  • 5z4y, 5z4z – PaTA NTD domain
    

• HlyU TA

• • 4k2e, 4ooi – VcTA
    
  • 3jth – VvTA
    
  • 5znx – VvTA + inhibitor
    

• ToxR TA

• • 6uue, 6utc – VvTA
    
  • 7nmb, 7nn6 – VcTA - NMR
    

• LysR TA

• • 5x0o – VvTA
    
  • 5x0n – VvTA (mutant)
    
  • 3t1b, 3szp – VcTA
    
  • 6tpr, 6z07, 6z17, 6z5k, 6yz3, 7o2t, 7o2u – PaTA + antagonist
    
  • 6yiz, 7nbw – PaTA + agonist
    
  • 5z7h – SaTA
    
  • 4pzj – TA – Eggerthella lenta
    
  • 3hhf, 3hhg, 4ab5 – NmTA
    
  • 3fzj – TA – Comamonas testosteroni
    
  • 1ixc, 1iz1 – CnTA – Cupriavidus necator
    
  • 5xxp, 7d98 – CnTA + DNA
    
  • 1uth, 2y7r, 5ae4 – TA – Burkholderia cepacia
    
  • 7trv, 7trw – TA LBD – Yersinia pestis
    
  • 7erp, 7erq – CsTA regulatory domain – Cronobacter sakazakii
    
  • 7fdf – CsTA regulatory domain (mutant)
    

• Aft2 TA

• • 4lmg – yTA + DNA
    

• Mga TA

• • 5way – SpTA – Streptococcus pneumoniae
    

• Spt7 TA

• • 6t9k, 6t9i – yTA in SAGA – Cryo EM
    

• Quorum-sensing TA or TraR

• • 5l07 – YeTA – Yersinia enterocolitica
    
  • 5l09 – YeTA + THF derivative
    
  • 1l3l – AtTA + pheromone + DNA – Agrobacterium tumefaciens
    
  • 1h0m – AtTA + auto-inducer + DNA
    

• MexT TA

• • 6l33 – PaTA regulatory domain
    

• ComR TA

• • 5juf, 6qer – StTA – Streptococcus thermophilus
    
  • 5jub – StTA + DNA
    
  • 5fd4 – TA – Streptococcus suis
    
  • 7n10, 7n1n – SmTA DBD + Prx – Streptococcus mutans
    
  • 6hu8 – SvTA – Streptococcus vestibularis
    
  • 6hua – SvTA + peptide
    

• FasR TA

• • 6o6p – MtTA + DNA – Mycobacterium tuberculosis
    
  • 6o6o – MtTA + myristic acid
    
  • 6o6n – MtTA + arachinoyl-CoA
    

• ModE TA

• • 1o7l, 1h9s – EcTA + Mo
    
  • 1b9m, 1b9n, 1h9r – EcTA + Ni
    

• TetR family TA

• • 1z77, 2id6, 2iek, 1zkg, 4i76, 3ih2, 3ih3, 3ih4 – TmTA – Thermotoga maritima
    
  • 4i6z – TmTA + DNA
    
  • 1zk8, 2fq4, 4me9 – BcTA – Bacillus cereus
    
  • 3cwr – TA – Rhodspirillum rubrum
    
  • 1z0x – EfTA – Enterococcus faecalis
    
  • 3c2b – AfTA – Agrobacterium fabrum
    
  • 2o7t – CgTA
    
  • 2g7s – AtTA
    
  • 3gzi – TA – Shewanella loihica
    
  • 2qib, 2zcx, 6srm – ScTA – Streptomyces coelicolor
    
  • 2hyt – TA – Pectobacterium atrosepticum
    
  • 3cdl – PsTA – Pseudomonas syringae
    
  • 3kkc – SaTA – Streptococcus agalactiae
    
  • 3nnr – TA – Marinobacter aquaeolei
    
  • 3on4 – TA – Legionella pneumophila
    
  • 3f1b – RjTA – Rhodococcus jostii
    
  • 3eup – TA – Cytophaga hutchinsonii
    
  • 3egq – TA – Archaeoglobus fulgidus
    
  • 4hku – LmTA – Listeria monocytogenes
    
  • 3nrg, 3qbm – TA – Chlotoflexus aurantiacus
    
  • 6nsr – PaTA (mutant) + DNA
    
  • 4jkz – MsTA – Mycobacterium smegmatis
    
  • 6el2 – SacTA – Sulfolobus acidocaldarius
    
  • 6en8 – SacTA + DNA
    

• TetR/AcrR family TA

• • 2rae – RjTA
    
  • 3lhq – StTA
    
  • 3b81 – CpTA – Clostridium acetobutylicum
    
  • 3dcf – TA – Thermobifida fusca
    
  • 3mvp – SmTA
    
  • 5d18, 5d19, 6a4l, 6a4w – MtTA
    
  • 2eh3 – TA – Aquifex aeolicus
    
  • 3vuq – TtTA – Thermus thermophilus
    
  • 7eqe – SgTA – Streptococcus griseus
    
  • 7eqf – SgTA + ligand
    
  • 5gp9, 5gpa – BhTA – Bacillus halodurans
    
  • 5gpc – BhTA + DNA
    
  • 6g87 – BdTA – Bradyrhizobium diazoefficiens
    
  • 6g8h – BdTA + naringenin
    
  • 6g8g – BdTA + genistein
    

• GntR family TA

• • 3l5z – BcTA
    
  • 3ddv – EfTA
    
  • 3fms, 3sxy – TmTA
    
  • 3c7j – PsTA
    
  • 2di3, 2p19 – CgTA
    
  • 3tqn – TA – Coxiella burnetii
    
  • 6za0, 6za3, 7za7 – AfTA
    
  • 6z74, 6zab – AfTA + DNA
    
  • 7u5q – TA – Brucella melitensis
    
  • 6sbs – SacTA
    
  • 3h5o – TA – Chromobacterium violaceum
    
  • 6az6, 7b5t, 7b5y, 7b5w – SaTA
    
  • 7b5u – SaTA + diAMP
    
  • 7oz3 – SaTA + DNA – Cryo EM
    
  • 4r1h – LmTA
    
  • 3ihu – TA – Ralstonia eutropha
    
  • 3lhe – TA – Bacillus anthracis
    
  • 3f8m – MsTA
    

• MarR family TA or multiple antibiotic resistance protein

• • 3boq, 3cjn, 3e6m – RpTA - Ruegeria pomeryi
    
  • 3s2w – TA – Methanosarcina mazei
    
  • 3bpv – TA – Methanobacterium thermoautotrophicum
    
  • 2fbk – DrTA – Deinococcus radiodurans
    
  • 5dd8 – DrTA (mutant)
    
  • 2fa5 – TA – Xanthomonas campestris
    
  • 3g3z, 5aiq – NmTA
    
  • 5aip – NmTA + hydroxyphenylacetate
    
  • 5e1w – DmTA – Dihalococcoides mccartyi
    
  • 5e1z, 5e1x, 5e20 – DmTA + phenol derivative
    
  • 6c28 – RpTA + coumaroyl-CoA – Rhodopseudomonas palustris
    
  • 3fm5 – RjTA
    
  • 1z91 – BsTA
    
  • 4b8x – ScTA
    
  • 4yif – MtTA
    
  • 3vb2, 3voe, 4jba – EcTA
    
  • 3vod – EcTA (mutant)
    
  • 5h3r – EcTA (mutant) + DNA
    
  • 5eri – CdTA – Clostridium difficile
    
  • 7dvn – TA + effector – Paenisporosarcina
    
  • 3u2r – TA – Planctopirus limnophilus
    
  • 2rdp – TA – Bacillus stearothermophilus
    

• MerR family TA or mercuric resistance operon regulatory protein

• • 3hh0 – BcTA
    
  • 3gpv – BtTA
    
  • 4ua1, 4ua2 – TA – Bacillus megaterium
    
  • 5crl – PaTA
    
  • 5gpe – TA – Cupriavidus metallidurans
    
  • 3cnb – TA – Colwellia psychrerythraea
    
  • 6d90 – HiTA – Haemophilia influenzae
    
  • 5d8c – HiTA + DNA
    
  • 6xl6, 6xla, 6xlk – EcTA + DNA – Cryo EM
    
  • 6xl5, 6xl9, 6xlj – EcTA in RNP complex – Cryo EM
    

• AsnC family TA

• • 3i4p – AfTA
    
  • 2cg4 – EcTA
    

• AraC family TA or arabinose operon regulatory protein

• • 3gra – PpTA – Pseudomonas putida
    
  • 3cu5 – TA – Lacnoclostridium phytofermentans
    
  • 5chh – PaTA
    
  • 2ara – EcTA
    
  • 1xja – EcTA dimerization domain (mutant)
    
  • 2k9s – EcTA DBD - NMR
    
  • 2arc – EcTA + arabinose
    
  • 2aac – EcTA + fucose
    

• LacI family TA

• • 3kjx, 3e3m – RpTA
    
  • 3jy6 – TA - Lactobacillus brevis
    
  • 6chk – LcTA - Lactobacillus casei
    
  • 4rk5, 4rk4 – LcTA + sugar
    
  • 4rk0, 4rk1 – EfTA + ribose
    
  • 3h5t – CgTA
    
  • 3kke – MsTA
    
  • 4rkq, 4rkr – TA - Arthrobacter
    

• PadR family TA

• • 5zhv, 5zi8, 5zhc – MtTA
    
  • 5zqh – SpTA
    
  • 5x12, 7cbv – BsTA
    
  • 5x13, 5y8t – BsTA + coumaric acid
    
  • 5x14 – BsTA + ferulic acid
    
  • 6abq, 6abt – LmTA
    
  • 5dym – CdTA
    

• TrmB TA or tRNA (guanine-N(7)-) methyltransferase

• • 2f5t – TA – Thermococcus litoralis
    
  • 3qph – PfTA + sucrose – Pyrococcus furiosus
    

• IclR TA

• • 1mkm – TmTA
    
  • 2o99, 2o9a – EcTA C-terminal
    
  • 1td5 – EcTA LBD
    
  • 7cuo – TA + hydroxybenzoate – Microbacterium hydrocarbonoxydans
    

• BgaR TA

• • 6nwo – CpTA – Clostridium perfringens
    
  • 6nx3, 6nwj, 6nwm, 6nwh – CpTA + pyranose derivative
    

• SlyA TA

• • 1lj9 – EfTA
    
  • 3qpt – StTA
    
  • 3q5f – StTA + DNA
    
  • 4aih – YpTA – Yersinia pseudotuberculosis
    
  • 4aij, 4aik – YpTA + DNA
    

• CouR TA

• • 5cyv, 6c28 – RjTA + coumaroyl-CoA – Rhodococcus jostii
    
  • 6c9t – RpTA
    
  • 6c2s – RpTA + DNA
    

• CueR TA

• • 1q07, 1q06, 1q05 – EcTA
    

• LuxR TA

• • 6wae – VvTA
    
  • 6wai, 6wah, 6wag, 6waf – VvTA (mutant)
    

• LuxT TA

• • 3b4s, 3ljl – VpTA
    

• ClgR TA or Clp gene regulator

• • 5woq – MsTA
    
  • 3f51, 3f52 – CgTA
    

• LmrR TA

• • 3f8b, 6i8n – LlTA – Lactococcus lactis
    
  • 3f8c, 3f8f – LlTA + drug
    
  • 6vwe, 6do0 – LlTA + Rh complex
    
  • 6r1l – LlTA + Cu + phenanthroline
    
  • [[4zzd] – LlTA + riboflavine
    
  • 6fuu – LlTA + heme
    

• MvfR TA

• • 4jvc, 6z17 – PaTA
    
  • 4jvd, 4jvi, 6q7u, 6q7v, 6tpr, 6yiz, 6yz3, 6z07, **6z17, 6z5k, 7nbw, 7o2t, 7o2u – PaTA + inhibitor
    
  • 6b8a, 6q7w – PaTA LBD 94-295 + inhibitor
    

• HdfR TA

• • 6wn5 – TA – Klebsiella pneumoniae
    

• McbR TA

• • 4p9f – EcTA
    
  • 4ab5 – MnTA
    
  • 4ab6 – MnTA (mutant)
    

• MetR TA

• • 5fo5 – EcTA DBD
    

• YvhJ TA

• • 3nxh – BsTA
    

• CgmR TA

• • 2yve, 2zoy – CgTA
    
  • 2zoz – CgTA + ethidium
    
  • 2yvh – CgTA + DNA
    

• AraR TA or arabinose metabolism transcriptional repressor

• • 5bs6, 5dd4 – BtTA – Bacterioides thetaiotaomicron
    
  • 3tb6 – BtTA effector-binding domain 71-362 + arabinose
    
  • 5ddg – BtTA + DNA
    
  • 5deq – BtTA 1-225 + arabinose
    
  • 4egy, 4egz, 4h0e, 5d4r, 5d4s – BsTA DBD 1-68 + DNA
    

• CarH TA or light-dependent transcriptional regulator

• • 5c8a, 5c8d, 5c8e, 5c8f – TtTA + cobalamin derivative
    

• ZitR TA or zinc transport transcriptional regulator

• • 5yhx – LlTA
    
  • 5yhy, 5yhz, 5yi0, 5yi1, 6fi9 – LlTA (mutant)
    
  • 5yi2 – LlTA + DNA
    
  • 5yi3 – LlTA (mutant) + DNA
    

• LsrR TA

• • 4l4y – EcTA
    
  • 4l4z, 4l50, 4l51, 4l5i, 4l5j – EcTA + ligand
    

• HTH-type TA or helix-turn-helix-type

• • 2uxu – PpTA TtgR + naringenin
    
  • 2uxh – PpTA TtgR + quercetin
    
  • 2uxi – PpTA TtgR + phloretin
    
  • 6ugl, 6kju – VcTA + pyrazine derivative
    
  • 2bv6 – SaTA MgrA – Staphylococcus aureus
    
  • 5hs5, 5ywj, 6k8e – SaTA SarX
    
  • 3hrm, 3hse – SaTA SarZ
    
  • 6r1p – MtTA EthR
    
  • 1ysq – EcTA YiaJ
    
  • 2qop, 3bcg – EcTA AcrR
    
  • 6ldi, 6xh7, 6xh8, 7c17 – EcTA CueR in transcription activation complex – Cryo EM
    
  • 4wls, 4wlw – EcTA CueR + DNA
    
  • 4x1e – EcTA RutR
    
  • 4xk4, 4jyk – EcTA RutR + uracil derivative
    
  • 2hxr – EcTA CynR LBD
    
  • 3hfu – EcTA CynR LBD + N3
    
  • 2gfn – RjTA Rha1
    
  • 1i1g – PfTA LrpA
    
  • 7cla – TA SkgA – Caulobacter vibrioides
    
  • 7bzd – BsTA HxlR
    
  • 7bze – BsTA HxlR (mutant)
    
  • 7bzg – BsTA HxlR + DNA
    
  • 7amn, 7amt – TA LuxR + DNA – Vibrio alginolyticus
    
  • 2dtz, 2hq5 – SaTA QacR (mutant)
    
  • 3bqz, 3br0, 3btc, 3btl – SaTA QacR (mutant) + malachite green
    
  • 3br1, 3br2, 3bt9, 3btj – SaTA QacR (mutant) + dequalinium
    
  • 3bti – SaTA QacR (mutant) + berberine
    
  • 1qvu,3br3, 3pm1 – SaTA QacR (mutant) + ethidium
    
  • 1rkw, 1rpw – SaTA QacR (mutant) + pentamadine
    
  • 1qvt – SaTA QacR (mutant) + proflavine
    
  • 3br5, 3br6 – SaTA QacR (mutant) + rhodamine
    
  • 2gby – SaTA QacR (mutant) + berenil
    
  • 2g0e – SaTA QacR (mutant) + drug
    
  • 3k1n – AbTA BenM – Acinetobacter baylyi
    
  • 3k1p – AbTA BenM (mutant)
    
  • 2f6g, 2f6p, 2f97 – AbTA BenM effector-binding domain 81-304
    
  • 3m1e – AbTA BenM DBD 1-87
    
  • 4ihs, 4iht – AbTA BenM effector-binding domain + DNA
    
  • 2f78, 2f7a, 2f7c – AbTA BenM effector-binding domain + effector
    
  • 2h9b – EfTA BenM (mutant)
    
  • 2f7b, 2h98 – AbTA CatM effector-binding domain
    
  • 3glb – AbTA CatM effector-binding domain (mutant)
    
  • 2f7c – AbTA CatM effector-binding domain + muconate
    
  • 2cfx – BsTA LrpC
    
  • 2gqq – EcTA LrpC
    
  • 6d2s, 6cyj, 6cz6, 6cyy – MtTA PrpR
    
  • 2pju – EcTA PrpR
    
  • 5t4k, 5t4j, 5t4l, 5x03 – BsTA GabR EBO domain + pyridine derivative
    
  • 4mgr, 4nob, 4tv7 – BsTA GabR
    
  • 6uxz – BsTA GabR + agonist
    
  • 5u9e, 5u93 – TA RhaR regulatory domain – Bacteria latreille
    
  • 5z49 – TA CmpR effector-binding domain + ribulose bisphosphate – Synechococcus elongatus
    
  • 3kos – CfTA AmpR effector binding domain – Citrobacter freundii
    
  • 3kot – CfTA AmpR effector binding domain (mutant)
    
  • 4wkm – CfTA AmpR effector binding domain + peptide
    
  • 5mmh – PaTA AmpR effector binding domain
    

}}