1h1k
From Proteopedia
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'''THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA''' | '''THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA''' | ||
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[[Category: Stuart, D I.]] | [[Category: Stuart, D I.]] | ||
[[Category: Sutton, G.]] | [[Category: Sutton, G.]] | ||
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Revision as of 15:18, 2 May 2008
THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA
Overview
Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff.
About this Structure
1H1K is a Single protein structure of sequence from Bluetongue virus. Full crystallographic information is available from OCA.
Reference
The core of bluetongue virus binds double-stranded RNA., Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI, J Virol. 2002 Sep;76(18):9533-6. PMID:12186935 Page seeded by OCA on Fri May 2 18:18:08 2008
